Influence of heparin and low molecular weight dextran on the patency of autogenous vein grafts. Vein grafts in the venous system

R. W. Hobson, R. D. Croom, N. M. Rich

Research output: Contribution to journalArticlepeer-review

29 Scopus citations

Abstract

The use of heparin and dextran 40 was evaluated in a study of the patency of autologous vein grafts in the canine femoral vein. The postoperative patency rate in 42 venous grafts was evaluated by venography. Patency was improved to 100% with postoperative dextran 40 but the difference was not statistically significant. No improvement in patency was seen with heparin at the critical three day interval. The overall patency rate was 83% three days following operation. Recanalization resulted in an improved patency rate of 97% 6 wk following operation. The importance of precise and meticulous operative technique is stressed.

Original languageEnglish
Pages (from-to)773-776
Number of pages4
JournalAnnals of surgery
Volume178
Issue number6
DOIs
StatePublished - 1973
Externally publishedYes

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