TY - JOUR
T1 - Influenza surveillance in Indonesia
T2 - 1999-2003
AU - Beckett, Charmagne G.
AU - Kosasih, Herman
AU - Ma'roef, Chairin
AU - Listiyaningsih, Erlin
AU - Elyazar, Iqbal R.F.
AU - Wuryadi, Suharyono
AU - Yuwono, Djoko
AU - McArdle, James L.
AU - Corwin, Andrew L.
AU - Porter, Kevin R.
N1 - Funding Information:
1US Naval Medical Research Unit Two, and 2National Institute of Health Research and Development, Indonesian Ministry of Health, Jakarta, Indonesia; and 3Naval Medical Research Center, Silver Spring, Maryland
Funding Information:
HI assays were performed using turkey or chicken RBCs to identify influenza virus serotypes. This was achieved by testing the isolates against standard known reference antisera (provided by the World Health Organization [WHO] Regional Collaborating Centre for Reference and Research on Influenza; Melbourne, Australia) raised against specific influenza A or B serotypes. The full strain designations for all reference viruses and antisera supplied in the annual WHO kits from 1999–2003 are available at http://www.influenzacentre.org. When possible, positive virus isolates were sent to the WHO Collaborating Influenza Reference Centre in Melbourne for confirmation.
PY - 2004/8/15
Y1 - 2004/8/15
N2 - Although influenza is recognized for its worldwide importance, little is known about the disease from tropical countries like Indonesia. From August 1999 through January 2003, a surveillance study was conducted in clinics at 6 sentinel locations. Adults (age, >14 years) and children (age, 4-14 years) presenting with respiratory symptoms suggestive of influenza were asked to enroll in the study. Nasal and pharyngeal swabs were examined by virus isolation, polymerase chain reaction, and rapid immunochromatographic tests. A total of 3079 specimens were collected from 1544 participants. Influenza infection was confirmed in 172 volunteers (11.1%) presenting with influenza-like illness. Influenza A (H1N1 and H3N2) and B viruses were detected at all sites. Peak prevalence tended to coincide with the respective rainy seasons, regardless of location. In light of the recent epidemic of severe acute respiratory syndrome, continued influenza surveillance would be useful in strengthening the infrastructure of the Indonesian public health system.
AB - Although influenza is recognized for its worldwide importance, little is known about the disease from tropical countries like Indonesia. From August 1999 through January 2003, a surveillance study was conducted in clinics at 6 sentinel locations. Adults (age, >14 years) and children (age, 4-14 years) presenting with respiratory symptoms suggestive of influenza were asked to enroll in the study. Nasal and pharyngeal swabs were examined by virus isolation, polymerase chain reaction, and rapid immunochromatographic tests. A total of 3079 specimens were collected from 1544 participants. Influenza infection was confirmed in 172 volunteers (11.1%) presenting with influenza-like illness. Influenza A (H1N1 and H3N2) and B viruses were detected at all sites. Peak prevalence tended to coincide with the respective rainy seasons, regardless of location. In light of the recent epidemic of severe acute respiratory syndrome, continued influenza surveillance would be useful in strengthening the infrastructure of the Indonesian public health system.
UR - http://www.scopus.com/inward/record.url?scp=4344665222&partnerID=8YFLogxK
U2 - 10.1086/422314
DO - 10.1086/422314
M3 - Article
C2 - 15356802
AN - SCOPUS:4344665222
SN - 1058-4838
VL - 39
SP - 443
EP - 449
JO - Clinical Infectious Diseases
JF - Clinical Infectious Diseases
IS - 4
ER -