Inhalation injury and toxic industrial chemical exposure

Omar Saeed, Nathan L. Boyer, Jeremy C. Pamplin, Ian R. Driscoll, Jeff DellaVolpe, Jeremy Cannon, Leopoldo C. Cancio

Research output: Contribution to journalArticlepeer-review

19 Scopus citations


Toxic industrial chemicals include chlorine, phosgene, hydrogen sulfide, and ammonia have variable effects on the respiratory tract, and maybe seen alone or in combination, secondary to inhalation injury. Other considerations include the effects of cyanide, carbon monoxide, and fire suppressants. This Clinical Practice Guideline (CPG) will provide the reader with a brief overview of these important topics and general management strategies for each as well as for inhalation injury. Chlorine, phosgene, hydrogen sulfide, and ammonia are either of intermediate or high water solubility leading to immediate reactions with mucous membranes of the face, throat, and lungs and rapid symptoms onset after exposure. The exception to rapid symptom onset is phosgene which may take up to a day to develop severe acute respiratory distress syndrome. Management of these patients includes early airway management, lungprotective ventilator strategies, aggressive pulmonary toilet, and avoidance of volume overload.

Original languageEnglish
Pages (from-to)130-132
Number of pages3
JournalMilitary Medicine
StatePublished - 2018
Externally publishedYes


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