TY - JOUR
T1 - Inhibition of Neisseria gonorrhoeae by Lactobacillus species that are commonly isolated from the female genital tract
AU - St. Amant, Diane C.
AU - Valentin-Bon, Iris E.
AU - Jerse, Ann E.
PY - 2002/12
Y1 - 2002/12
N2 - Epidemiological studies suggest H2O2-producing lactobacilli protect women against gonorrhea. Here we demonstrate that Lactobacillus crispatus and Lactobacillus jensenii, the most common lactobacilli in the female genital tract, inhibit gonococci in both acidic and neutral pH conditions. Inhibition was neutralized by bovine catalase, suggesting that H2O2 is the primary mediator of inhibition.
AB - Epidemiological studies suggest H2O2-producing lactobacilli protect women against gonorrhea. Here we demonstrate that Lactobacillus crispatus and Lactobacillus jensenii, the most common lactobacilli in the female genital tract, inhibit gonococci in both acidic and neutral pH conditions. Inhibition was neutralized by bovine catalase, suggesting that H2O2 is the primary mediator of inhibition.
UR - http://www.scopus.com/inward/record.url?scp=0036892987&partnerID=8YFLogxK
U2 - 10.1128/IAI.70.12.7169-7171.2002
DO - 10.1128/IAI.70.12.7169-7171.2002
M3 - Article
C2 - 12438404
AN - SCOPUS:0036892987
SN - 0019-9567
VL - 70
SP - 7169
EP - 7171
JO - Infection and Immunity
JF - Infection and Immunity
IS - 12
ER -