Inhibition of Neisseria gonorrhoeae by Lactobacillus species that are commonly isolated from the female genital tract

Diane C. St. Amant; Iris E. Valentin-Bon; Ann E. Jerse

doi:10.1128/IAI.70.12.7169-7171.2002

Inhibition of Neisseria gonorrhoeae by Lactobacillus species that are commonly isolated from the female genital tract

Diane C. St. Amant, Iris E. Valentin-Bon, Ann E. Jerse^*

^*Corresponding author for this work

Microbiology and Immunology

Research output: Contribution to journal › Article › peer-review

61 Scopus citations

Abstract

Epidemiological studies suggest H₂O₂-producing lactobacilli protect women against gonorrhea. Here we demonstrate that Lactobacillus crispatus and Lactobacillus jensenii, the most common lactobacilli in the female genital tract, inhibit gonococci in both acidic and neutral pH conditions. Inhibition was neutralized by bovine catalase, suggesting that H₂O₂ is the primary mediator of inhibition.

Original language	English
Pages (from-to)	7169-7171
Number of pages	3
Journal	Infection and Immunity
Volume	70
Issue number	12
DOIs	https://doi.org/10.1128/IAI.70.12.7169-7171.2002
State	Published - Dec 2002

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10.1128/IAI.70.12.7169-7171.2002

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title = "Inhibition of Neisseria gonorrhoeae by Lactobacillus species that are commonly isolated from the female genital tract",

abstract = "Epidemiological studies suggest H2O2-producing lactobacilli protect women against gonorrhea. Here we demonstrate that Lactobacillus crispatus and Lactobacillus jensenii, the most common lactobacilli in the female genital tract, inhibit gonococci in both acidic and neutral pH conditions. Inhibition was neutralized by bovine catalase, suggesting that H2O2 is the primary mediator of inhibition.",

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AU - Jerse, Ann E.

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AB - Epidemiological studies suggest H2O2-producing lactobacilli protect women against gonorrhea. Here we demonstrate that Lactobacillus crispatus and Lactobacillus jensenii, the most common lactobacilli in the female genital tract, inhibit gonococci in both acidic and neutral pH conditions. Inhibition was neutralized by bovine catalase, suggesting that H2O2 is the primary mediator of inhibition.

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Inhibition of Neisseria gonorrhoeae by Lactobacillus species that are commonly isolated from the female genital tract

Abstract

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