Initial and Long-term Results in the Management of Primary Chest Wall Neoplasms

Geoffrey M. Graeber*, Robert J. Snyder, Arthur W. Fleming, Harold D. Head, Frederick C. Lough, John S. Parker, Rostik Zajtchuk, Walter H. Brott

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

79 Scopus citations


One hundred ten patients with primary chest wall neoplasms were analyzed for long-term results. The diagnosis of 59 malignant and 51 benign tumors was confirmed by the Armed Forces Institute of Pathology. No deaths were associated with primary definitive therapy. Among the five most frequently encountered malignant tumor types, five-year survivals were obtained in 9 of 17 (53%) patients with fibrosarcoma, 8 of 9 (89%) patients with chondrosarcoma, 2 of 8 (25%) patients with solitary chest wall plasmacytoma (multiple myeloma), 1 of 6 (17%) patients with Ewing's sarcoma, and 2 of 4 (50%) of patients with osteogenic sarcoma. Although the five-year survival appears to indicate therapeutic success in patients with Ewing's sarcoma and osteogenic sarcoma, patients with chondrosarcoma or fibrosarcoma may have a more protracted course, and those with solitary plasmacytoma usually develop multiple myeloma. The findings suggest that radical surgical excision is the treatment of choice for chondrosarcoma; radical surgical excision combined with chemotherapy, for fibrosarcoma and osteogenic sarcoma; surgical excision combined with radiation and chemotherapy, for Ewing's sarcoma; and systemic surveillance and therapy, for pathologically confirmed solitary plasmacytoma.

Original languageEnglish
Pages (from-to)664-673
Number of pages10
JournalAnnals of Thoracic Surgery
Issue number6
StatePublished - 1982
Externally publishedYes


Dive into the research topics of 'Initial and Long-term Results in the Management of Primary Chest Wall Neoplasms'. Together they form a unique fingerprint.

Cite this