Abstract
The most challenging aspect of Post-Acute Sequelae of SARS-CoV-2 Infection (PASC) or Long COVID remains for the discordance between the viral damage from acute infection in the recent past and susceptibility of Long COVID without clear evidence of post infectious inflammation or autoimmune reactions. In this communication we propose that disarray of pericytes plays a central role in emerge of Long COVID. We assume pericytes are agents with “Triple-A” qualities, i.e., analyze-adapt and advance, necessary for sustainability of host homeostasis. Based on this view, we further suggest Long COVID may provide a model system to integrate system theory and complex adaptive systems to explore a new class of maladies those are currently not well defined and with no remedies.
| Original language | English |
|---|---|
| Article number | 572 |
| Journal | Journal of Clinical Medicine |
| Volume | 11 |
| Issue number | 3 |
| DOIs | |
| State | Published - 1 Feb 2022 |
Keywords
- Complex dynamical systems
- Emergent systems intelligence
- Entropy
- Long COVID
- Pericyte
- Triple-A
Fingerprint
Dive into the research topics of 'Is Long COVID a State of Systemic Pericyte Disarray?'. Together they form a unique fingerprint.Cite this
- APA
- Author
- BIBTEX
- Harvard
- Standard
- RIS
- Vancouver