TY - JOUR
T1 - Ischemic Complications of Distal Aortic Dissections
T2 - Open Surgical or Endovascular Management?
AU - Rasmussen, Todd E.
AU - Panneton, Jean M.
PY - 2001/9
Y1 - 2001/9
N2 - Acute aortic dissection is one of the most common catastrophic events that affects the aorta, and, even in the best of circumstances, morbidity and mortality remain high. The majority of aortic dissections involving the descending thoracic aorta can be successfully managed with medical therapy. However, even with aggressive medical therapy, the associated mortality approaches 20%, and a significant number of patients die within a year from complications related to the dissection. Operations for descending thoracic aortic dissection are reserved for patients who fail medical management and develop complications such as aneurysm formation, aortic rupture, branch vessel malperfusion, or refractory pain. Patients who require operative intervention for acute descending thoracic aortic dissections have a worse outcome, with mortality rates near 35%. Mortality is higher in patients who require operative intervention specifically for ischemic complications related to dissection. It is in this group of patients that new, less-invasive methods of endovascular treatment have been promoted with great enthusiasm. Furthermore, early success of endovascular techniques in treating ischemic complications of distal aortic dissection raises the question: Should such patients be managed with traditional open surgical operation or newer endovascular therapies? This article summarizes the anatomy and natural history of descending thoracic aortic dissection, focusing on the development of ischemic complications, comparing and contrasting the role of open surgical operation to endovascular therapy.
AB - Acute aortic dissection is one of the most common catastrophic events that affects the aorta, and, even in the best of circumstances, morbidity and mortality remain high. The majority of aortic dissections involving the descending thoracic aorta can be successfully managed with medical therapy. However, even with aggressive medical therapy, the associated mortality approaches 20%, and a significant number of patients die within a year from complications related to the dissection. Operations for descending thoracic aortic dissection are reserved for patients who fail medical management and develop complications such as aneurysm formation, aortic rupture, branch vessel malperfusion, or refractory pain. Patients who require operative intervention for acute descending thoracic aortic dissections have a worse outcome, with mortality rates near 35%. Mortality is higher in patients who require operative intervention specifically for ischemic complications related to dissection. It is in this group of patients that new, less-invasive methods of endovascular treatment have been promoted with great enthusiasm. Furthermore, early success of endovascular techniques in treating ischemic complications of distal aortic dissection raises the question: Should such patients be managed with traditional open surgical operation or newer endovascular therapies? This article summarizes the anatomy and natural history of descending thoracic aortic dissection, focusing on the development of ischemic complications, comparing and contrasting the role of open surgical operation to endovascular therapy.
KW - Aortic dissections
KW - aortic fenestration
KW - ischemic complications
KW - surgical repair
UR - http://www.scopus.com/inward/record.url?scp=84993690286&partnerID=8YFLogxK
U2 - 10.1177/153100350101400210
DO - 10.1177/153100350101400210
M3 - Article
AN - SCOPUS:84993690286
SN - 1531-0035
VL - 14
SP - 57
EP - 71
JO - Perspectives in Vascular Surgery and Endovascular Therapy
JF - Perspectives in Vascular Surgery and Endovascular Therapy
IS - 2
ER -