Isolated urethral metastasis from appendiceal mucinous adenocarcinoma

Pamela I. Causa Andrieu*, Jennifer S. Golia Pernicka, Gabriela Faria e Silva Costa, Gregory T. Chesnut, Jaspreet S. Shandu, Chen Ying-Bei, Iva Petkovska

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


We are presenting a compelling case of a 61-year-old female with a history of appendiceal mucinous adenocarcinoma (AMA) with a new complaint of irritative lower urinary tract symptoms. Magnetic resonance imaging (MRI) showed a semi-circumferential, T2 hyperintense, rim enhancing, and lacking restricted diffusion lesion involving the urethra and infiltrating the right perineal and internal obturator muscles. The suspected differential diagnosis was urethral malignancy, based on her cancer history and MRI findings. After interdisciplinary consensus, the patient underwent excision of the lesion, and pathology was consistent with metastasis from the primary tumor. The urethra is a rare site of primary malignancy and metastatic disease. In particular, a non-contiguous metastatic disease involving the urethra is exceedingly rare. To the best of our knowledge, this is the first report of an AMA metastasizing to the urethra.

Original languageEnglish
Pages (from-to)68-71
Number of pages4
JournalClinical Imaging
StatePublished - Nov 2020
Externally publishedYes


  • Adenocarcinoma, mucinous
  • Appendiceal neoplasms
  • Magnetic resonance imaging
  • Urethral neoplasms


Dive into the research topics of 'Isolated urethral metastasis from appendiceal mucinous adenocarcinoma'. Together they form a unique fingerprint.

Cite this