Left ventricular assist device decommissioning compared with explantation for ventricular recovery: A systematic review

Jae Hwan Choi, Matthew P. Weber, Dylan P. Horan, Jessica G.Y. Luc, Kevin Phan, Sinal Patel, Syed Saif Abbas Rizvi, Elizabeth J. Maynes, Gordon R. Reeves, John W. Entwistle, Rohinton J. Morris, H. Todd Massey, Vakhtang Tchantchaleishvili*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

22 Scopus citations

Abstract

Left ventricular assist device (LVAD) withdrawal with ventricular recovery represents the optimal outcome for patients previously implanted with an LVAD. The aim of this systematic review was to examine the patient outcomes of device withdrawal via minimally invasive pump decommissioning as compared with reoperation for pump explantation. An electronic search was performed to identify all studies in the English literature assessing LVAD withdrawal. All identified articles were systematically assessed for inclusion and exclusion criteria. Overall, 44 studies (85 patients) were included in the analysis, of whom 20% underwent decommissioning and 80% underwent explantation. The most commonly used LVAD types included the HeartMate II (decommissioning 23.5% vs. explantation 60.3%; p = 0.01) and HeartWare HVAD (decommissioning 76.5% vs. explantation 17.6%; p < 0.001). At median follow-up of 389 days, there were no significant differences in the incidence of cerebrovascular accidents (p = 0.88), infection (p = 0.75), and survival (p = 0.20). However, there was a trend toward a higher recurrence of heart failure in patients who underwent decommissioning as compared with explantation (decommissioning 15.4% vs. explantation 8.2%, cumulative hazard; p = 0.06). Decommissioning appears to be a feasible alternative to LVAD explantation in terms of overall patient outcomes.

Original languageEnglish
Pages (from-to)17-22
Number of pages6
JournalASAIO Journal
Volume66
Issue number1
DOIs
StatePublished - 1 Jan 2020
Externally publishedYes

Keywords

  • HeartMate II
  • continuous flow left ventricular devices
  • minimally invasive pump decommissioning
  • pump decommissioning

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