Life-threatening polyneuropathy heralding renal cell carcinoma

Michael J. Roy*, Eugene F. May, Bahman Jabbari

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Objective: To report the occurrence of life-threatening poly- neuropathy in association with renal cell carcinoma. Methods: Case report and review of the medical literature. Results: A 65-year-old man developed a fulminant, life-threatening sensory motor polyneuropathy several months before renal cell carcinoma was identified. Dramatic symptomatic improvement ensued after treatment with intravenous immunoglobulin, although the patient succumbed to complications of the tumor years later. Conclusions: Chronic sensory motor polyneuropathy is a known paraneoplastic syndrome associated with renal cell carcinoma. This report emphasizes that in rare conditions, the polyneuropathy could take an acute demyelinating form, which is important for clinicians to recognize.

Original languageEnglish
Pages (from-to)986-989
Number of pages4
JournalMilitary Medicine
Issue number12
StatePublished - 1 Dec 2002
Externally publishedYes


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