TY - JOUR
T1 - Lifetime total and beverage specific - Alcohol intake and prostate cancer risk
T2 - A case-control study
AU - Barba, Maddalena
AU - McCann, Susan E.
AU - Schünemann, Holger J.
AU - Stranges, Saverio
AU - Fuhrman, Barbara
AU - De Placido, Sabino
AU - Carruba, Giuseppe
AU - Freudenheim, Jo L.
AU - Trevisan, Maurizio
AU - Russell, Marcia
AU - Nochajski, Tom
AU - Muti, Paola
PY - 2004/12/9
Y1 - 2004/12/9
N2 - Background: We investigated lifetime alcohol consumption and prostate cancer risk in a case-control study conducted in Buffalo, NY (1998-2001). Methods: The study included 88 men, aged 45 to 85 years with incident, histologically-confirmed prostate cancer and 272 controls. We conducted extensive in-person interviews regarding lifetime alcohol consumption and other epidemiologic data. Results: Prostate cancer risk was not associated with lifetime intake of total and beverage specific ethanol. In addition we found no association with number of drinks per day (average drinks per day over the lifetime) or drinks per drinking day (average drinks per day on drinking days only over the lifetime). However, we observed an inverse association with the total number of drinking years. Men in the lowest tertile of total drinking years had a two-fold prostate cancer risk than men in the highest tertile (OR 2.16, 95% CI 0.98-4.78, p for trend <0.05). Conclusion: Our results suggest that alcohol intake distribution across lifetime may play a more important role in prostate cancer etiology than total lifetime consumption.
AB - Background: We investigated lifetime alcohol consumption and prostate cancer risk in a case-control study conducted in Buffalo, NY (1998-2001). Methods: The study included 88 men, aged 45 to 85 years with incident, histologically-confirmed prostate cancer and 272 controls. We conducted extensive in-person interviews regarding lifetime alcohol consumption and other epidemiologic data. Results: Prostate cancer risk was not associated with lifetime intake of total and beverage specific ethanol. In addition we found no association with number of drinks per day (average drinks per day over the lifetime) or drinks per drinking day (average drinks per day on drinking days only over the lifetime). However, we observed an inverse association with the total number of drinking years. Men in the lowest tertile of total drinking years had a two-fold prostate cancer risk than men in the highest tertile (OR 2.16, 95% CI 0.98-4.78, p for trend <0.05). Conclusion: Our results suggest that alcohol intake distribution across lifetime may play a more important role in prostate cancer etiology than total lifetime consumption.
UR - http://www.scopus.com/inward/record.url?scp=20044362007&partnerID=8YFLogxK
U2 - 10.1186/1475-2891-3-23
DO - 10.1186/1475-2891-3-23
M3 - Article
AN - SCOPUS:20044362007
SN - 1475-2891
VL - 3
JO - Nutrition Journal
JF - Nutrition Journal
ER -