Local reactions from subcutaneous allergen immunotherapy

Christopher A. Coop*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


Local reactions from subcutaneous allergen immunotherapy are very common during the course of immunotherapy. These local reactions are not bothersome to patients. Local reactions from immunotherapy also do not predict future local or systemic reactions. This review discusses the studies that show that local reactions are not predictive of future reactions and that dose adjustments for local reactions from allergen immunotherapy are unnecessary. The article also focuses on factors that lead to patient noncompliance with immunotherapy and evaluates methods to prevent local reactions from subcutaneous allergen immunotherapy.

Original languageEnglish
Pages (from-to)1339-1345
Number of pages7
Issue number12
StatePublished - Dec 2013
Externally publishedYes


  • allergen immunotherapy
  • local reactions
  • systemic reactions


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