Macrocytosis after nucleoside-containing HIV treatment regimens

Kyle Petersen*, Braden R. Hale, Mark R. Wallace

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Macrocytosis occurs with HIV therapies containing zidovudine (AZT) and stavudine (d4T) and may help assess adherence. Occurrence in antiretroviral therapy regimens without these agents or when they are added to multidrug antiretroviral therapy is unknown. We retrospectively evaluated change in mean corpuscular volume for 590 patients at 90 days after initiating therapy. Zidovudine and stavudine caused significant increases in mean corpuscular volume, similar to previous studies, whereas didanosine (ddI) did not. Addition of a protease inhibitor and or lamivudine did not significantly change the mean corpuscular volume.

Original languageEnglish
Pages (from-to)65-67
Number of pages3
JournalInfectious Diseases in Clinical Practice
Issue number2
StatePublished - Mar 2005
Externally publishedYes


Dive into the research topics of 'Macrocytosis after nucleoside-containing HIV treatment regimens'. Together they form a unique fingerprint.

Cite this