The momentum produced by the sequencing of the human genome has rapidly spilled over into the study of gene transcripts, proteins, and small molecule metabolites. The current trend in biology is no longer to study individ- ual components, but to study the cell as a whole. This trend has not only spawned several new technologies (i.e., cDNA and protein arrays), but also has brought about the realization of unrecognized utilities possessed by existing technologies (i.e., metabonomics analysis using nuclear magnetic resonance spectroscopy). One of the largest trends is the development of methods to analyze large numbers of proteins in single experiments. These so-called “proteomics” approaches provide a powerful means to examine global changes in protein levels and expression under changing environmental conditions.
|Title of host publication||Analytical Instrumentation Handbook, Third Edition|
|Number of pages||15|
|State||Published - 1 Jan 2004|