Mass spectrometry instrumentation

Li Rong Yu, Thomas P. Conrads, Timothy D. Veenstra

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

2 Scopus citations


The momentum produced by the sequencing of the human genome has rapidly spilled over into the study of gene transcripts, proteins, and small molecule metabolites. The current trend in biology is no longer to study individ- ual components, but to study the cell as a whole. This trend has not only spawned several new technologies (i.e., cDNA and protein arrays), but also has brought about the realization of unrecognized utilities possessed by existing technologies (i.e., metabonomics analysis using nuclear magnetic resonance spectroscopy). One of the largest trends is the development of methods to analyze large numbers of proteins in single experiments. These so-called “proteomics” approaches provide a powerful means to examine global changes in protein levels and expression under changing environmental conditions.

Original languageEnglish
Title of host publicationAnalytical Instrumentation Handbook, Third Edition
PublisherCRC Press
Number of pages15
ISBN (Electronic)9780849390395
ISBN (Print)9780824753481
StatePublished - 1 Jan 2004
Externally publishedYes


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