Abstract
Fourteen Enterobacteriaceae isolates with ertapenem MIC >2 mg/mL were analyzed to identify mechanisms of resistance. All isolates produced extended-spectrum β-lactamase or AmpC β-lactamase with variable, but decreased, expression of outer membrane proteins. One Enterobacter cloacae produced derepressed AmpC β-lactamase, 1 Escherichia coli expressed plasmid-mediated AmpC β-lactamase, and 1 E. cloacae produced a carbapenemase.
Original language | English |
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Pages (from-to) | 445-448 |
Number of pages | 4 |
Journal | Diagnostic Microbiology and Infectious Disease |
Volume | 66 |
Issue number | 4 |
DOIs | |
State | Published - Apr 2010 |
Keywords
- AmpC beta-lactamase
- Carbapenem
- Enterobacteriaceae
- Extended spectrum beta-lactamases
- KPC-2
- Porins
- Texas city