Meiotic spindle pushed outward by inward organelle packing

Xin Xiang

doi:10.1016/j.tcb.2025.03.006

Meiotic spindle pushed outward by inward organelle packing

Xin Xiang^*

^*Corresponding author for this work

Biochemistry

Research output: Contribution to journal › Short survey › peer-review

Abstract

In Caenorhabditis elegans oocytes, meiotic spindle movement toward the cortex before anaphase depends on kinesin-1. A recent study by Aquino et al. uncovers a novel mechanism whereby the inward organelle packing driven by kinesin-1 excludes the spindle from the center, thereby causing it to be positioned near the cortex.

Original language	English
Pages (from-to)	357-358
Number of pages	2
Journal	Trends in Cell Biology
Volume	35
Issue number	5
DOIs	https://doi.org/10.1016/j.tcb.2025.03.006
State	Published - May 2025

Keywords

C. elegans oocyte
kinesin-1
microtubule polarity
organelle movement
spindle positioning
volume exclusion

Access to Document

10.1016/j.tcb.2025.03.006

Cite this

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title = "Meiotic spindle pushed outward by inward organelle packing",

abstract = "In Caenorhabditis elegans oocytes, meiotic spindle movement toward the cortex before anaphase depends on kinesin-1. A recent study by Aquino et al. uncovers a novel mechanism whereby the inward organelle packing driven by kinesin-1 excludes the spindle from the center, thereby causing it to be positioned near the cortex.",

keywords = "C. elegans oocyte, kinesin-1, microtubule polarity, organelle movement, spindle positioning, volume exclusion",

author = "Xin Xiang",

note = "Publisher Copyright: {\textcopyright} 2025",

year = "2025",

month = may,

doi = "10.1016/j.tcb.2025.03.006",

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T1 - Meiotic spindle pushed outward by inward organelle packing

AU - Xiang, Xin

PY - 2025/5

Y1 - 2025/5

N2 - In Caenorhabditis elegans oocytes, meiotic spindle movement toward the cortex before anaphase depends on kinesin-1. A recent study by Aquino et al. uncovers a novel mechanism whereby the inward organelle packing driven by kinesin-1 excludes the spindle from the center, thereby causing it to be positioned near the cortex.

AB - In Caenorhabditis elegans oocytes, meiotic spindle movement toward the cortex before anaphase depends on kinesin-1. A recent study by Aquino et al. uncovers a novel mechanism whereby the inward organelle packing driven by kinesin-1 excludes the spindle from the center, thereby causing it to be positioned near the cortex.

KW - C. elegans oocyte

KW - kinesin-1

KW - microtubule polarity

KW - organelle movement

KW - spindle positioning

KW - volume exclusion

UR - http://www.scopus.com/inward/record.url?scp=105003180142&partnerID=8YFLogxK

U2 - 10.1016/j.tcb.2025.03.006

DO - 10.1016/j.tcb.2025.03.006

M3 - Short survey

C2 - 40221342

AN - SCOPUS:105003180142

SN - 0962-8924

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SP - 357

EP - 358

JO - Trends in Cell Biology

JF - Trends in Cell Biology

IS - 5

ER -