TY - JOUR
T1 - Metabolic characteristics of youth with loss of control eating
AU - Radin, Rachel M.
AU - Tanofsky-Kraff, Marian
AU - Shomaker, Lauren B.
AU - Kelly, Nichole R.
AU - Pickworth, Courtney K.
AU - Shank, Lisa M.
AU - Altschul, Anne M.
AU - Brady, Sheila M.
AU - Demidowich, Andrew P.
AU - Yanovski, Susan Z.
AU - Hubbard, Van S.
AU - Yanovski, Jack A.
N1 - Funding Information:
Funding for this study was provided by the following sources: Intramural Research Program Grant 1ZIAHD000641 from the NICHD (to J.A.Y.) with supplemental funding from the National Institute for Minority Health and Health Disparities (NIMHD) ( 1ZIAHD00641 ), Office of Behavioral and Social Science Research, the Office of Disease Prevention, and the Division of Nutrition Research Coordination, NIH ( 1ZIAHD00641 ) (to J.A.Y.), NIH; K99/R00HD069516 from NICHD (to L.B.S.), and F32HD056762 from NICHD (to L.B.S.); USUHS grant R072IC (to M.T.K.), and NIDDK grant R01DK080906-04 (to M.T.K.). The above funding sources and agencies (NICHD, NIMHD, NIDDK, and USUHS) had no role in the study design, collection, analysis or interpretation of the data, writing of the manuscript, or the decision to submit the paper for publication. The opinions and assertions expressed herein are those of the authors and are not to be construed as reflecting the views of the PHS, USUHS, or the U.S. Department of Defense.
Publisher Copyright:
© 2015.
PY - 2015/12/1
Y1 - 2015/12/1
N2 - Purpose: Preliminary data in adults suggest that binge eating is associated with greater prevalence of metabolic syndrome (MetS) components. However, there are limited data in youth, and little is known of the role of binge episode size in these relationships. Methods: We examined the relationship between loss of control eating and metabolic characteristics in a convenience sample of 329 treatment-seeking and non-treatment-seeking adolescent boys and girls. The sample was enriched by design with adolescents who were overweight or obese and with individuals who reported episodes of loss of control over their eating (either objectively large binge episodes, OBEs or subjectively large binge episodes, SBEs, in the past month), as assessed by clinical interview. MetS components (blood pressure, lipids, glucose, and waist circumference) were the primary variables of interest. Results: 46% of the cohort reported loss of control eating; among those, 53% reported SBEs only and 47% reported OBEs. Youth with loss of control eating had higher systolic blood pressure (p= .001) and higher low-density lipoprotein cholesterol (LDL-c) (p= .002) compared to those without loss of control eating, in analyses adjusted for intervention-seeking status, fat mass and sociodemographic characteristics. Youth reporting OBEs had higher LDL-c (p= .013) compared to those reporting only SBEs. Conclusions: Adolescents reporting loss of control episodes had greater dysfunction in some components of the MetS compared to youth without loss of control; episode size may contribute to metabolic dysfunction.
AB - Purpose: Preliminary data in adults suggest that binge eating is associated with greater prevalence of metabolic syndrome (MetS) components. However, there are limited data in youth, and little is known of the role of binge episode size in these relationships. Methods: We examined the relationship between loss of control eating and metabolic characteristics in a convenience sample of 329 treatment-seeking and non-treatment-seeking adolescent boys and girls. The sample was enriched by design with adolescents who were overweight or obese and with individuals who reported episodes of loss of control over their eating (either objectively large binge episodes, OBEs or subjectively large binge episodes, SBEs, in the past month), as assessed by clinical interview. MetS components (blood pressure, lipids, glucose, and waist circumference) were the primary variables of interest. Results: 46% of the cohort reported loss of control eating; among those, 53% reported SBEs only and 47% reported OBEs. Youth with loss of control eating had higher systolic blood pressure (p= .001) and higher low-density lipoprotein cholesterol (LDL-c) (p= .002) compared to those without loss of control eating, in analyses adjusted for intervention-seeking status, fat mass and sociodemographic characteristics. Youth reporting OBEs had higher LDL-c (p= .013) compared to those reporting only SBEs. Conclusions: Adolescents reporting loss of control episodes had greater dysfunction in some components of the MetS compared to youth without loss of control; episode size may contribute to metabolic dysfunction.
KW - Adolescence
KW - Binge eating
KW - Loss of control eating
KW - Metabolic dysfunction
UR - http://www.scopus.com/inward/record.url?scp=84937684522&partnerID=8YFLogxK
U2 - 10.1016/j.eatbeh.2015.07.002
DO - 10.1016/j.eatbeh.2015.07.002
M3 - Article
C2 - 26210388
AN - SCOPUS:84937684522
SN - 1471-0153
VL - 19
SP - 86
EP - 89
JO - Eating Behaviors
JF - Eating Behaviors
ER -