Multilaminate resorbable biomedical device under biaxial loading

B. A. Whitson, B. C. Cheng, K. Kokini*, S. F. Badylak, U. Patel, R. Morff, C. R. O'Keefe

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

40 Scopus citations


The design and test of a multilaminate sheet developed for a hernia repair application is presented. As biomaterial applications become more complex, characterization of uniaxial properties becomes insufficient and biaxial testing becomes necessary. A measure of the in-plane biaxial strength of the device is inferred from a ball burst test. The results of this test for different thicknesses of the device are correlated with the uniaxial strength of the material. A biaxial test such as the ball burst test is more indicative of the properties of a planar material than would be a uniaxial test. The interactions in the biaxial mode of failure are of value and can be related back to a classical uniaxial tensile test from the ball burst test. The material used in this study to fabricate the device was a resorbable biomaterial called small intestinal submucosa (SIS). The effects of rehydration on the stiffness and associated ball burst properties of the SIS device were also measured. It is shown that at a rehydration time of 5 min from a reference dry state, steady-state mechanical properties are reached.

Original languageEnglish
Pages (from-to)277-281
Number of pages5
JournalJournal of Biomedical Materials Research
Issue number3
StatePublished - 1998
Externally publishedYes


  • Ball burst test
  • Biaxial testing
  • Multilaminate sheet
  • Rehydration effects
  • Small intestinal submucosa


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