Multiple Sclerosis Brain Lesion Segmentation with Different Architecture Ensembles

Pouria Tohidi*, Samuel W. Remedios, Danielle L. Greenman, Muhan Shao, Shuo Han, Blake E. Dewey, Jacob C. Reinhold, Yi Yu Chou, Dzung L. Pham, Jerry L. Prince, Aaron Carass

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations

Abstract

White matter lesion (WML) segmentation applied to magnetic resonance imaging (MRI) scans of people with multiple sclerosis has been an area of extensive research in recent years. As with most tasks in medical imaging, deep learning (DL) methods have proven very effective and have quickly replaced existing methods. Despite the improvement offered by these networks, there are still shortcomings with these DL approaches. In this work, we compare several DL algorithms, as well as methods for ensembling the results of those algorithms, for performing MS lesion segmentation. An ensemble approach is shown to best estimate total WML and has the highest agreement with manual delineations.

Original languageEnglish
Title of host publicationMedical Imaging 2022
Subtitle of host publicationBiomedical Applications in Molecular, Structural, and Functional Imaging
EditorsBarjor S. Gimi, Andrzej Krol
PublisherSPIE
ISBN (Electronic)9781510649477
DOIs
StatePublished - 2022
EventMedical Imaging 2022: Biomedical Applications in Molecular, Structural, and Functional Imaging - Virtual, Online
Duration: 21 Mar 202227 Mar 2022

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume12036
ISSN (Print)1605-7422

Conference

ConferenceMedical Imaging 2022: Biomedical Applications in Molecular, Structural, and Functional Imaging
CityVirtual, Online
Period21/03/2227/03/22

Keywords

  • deep learning
  • ensemble
  • MRI
  • multiple sclerosis
  • neuroimaging
  • segmentation
  • white matter lesions

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