Abstract
Cesium-137, becoming a more readily available ionizing gamma radiation source for laboratory use, was shown to effectively attenuate Schistosoma mansoni cercariae for vaccine production. In parallel comparison studies with the murine model, cesium-137 attenuated cercariae consistently afforded better (P > 0.05) protection than did the cobalt-60 prepared vaccine. Dose-response data indicated that the optimal total irradiation with cesium-137 was between 45 and 50 Krad.
Original language | English |
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Pages (from-to) | 398-402 |
Number of pages | 5 |
Journal | Journal of Parasitology |
Volume | 70 |
Issue number | 3 |
DOIs | |
State | Published - 1984 |
Externally published | Yes |