Myocardial Assessment with Cardiac CT: Ischemic Heart Disease and Beyond

Bryan C. Ramsey, Emilio Fentanes, Andrew D. Choi, Kelley R. Branch, Dustin M. Thomas*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


Purpose of Review: The aim of this review is to highlight recent advancements, current trends, and the expanding role for cardiac CT (CCT) in the evaluation of ischemic heart disease, nonischemic cardiomyopathies, and some specific congenital myocardial disease states. Recent Findings: CCT is a highly versatile imaging modality for the assessment of numerous cardiovascular disease states. Coronary CT angiography (CCTA) is now a well-established first-line imaging modality for the exclusion of significant coronary artery disease (CAD); however, CCTA has modest positive predictive value and specificity for diagnosing obstructive CAD in addition to limited capability to evaluate myocardial tissue characteristics. Summary: CTP, when combined with CCTA, presents the potential for full functional and anatomic assessment with a single modality. CCT is a useful adjunct in select patients to both TTE and CMR in the evaluation of ventricular volumes and systolic function. Newer applications, such as dynamic CTP and DECT, are promising diagnostic tools offering the possibility of more quantitative assessment of ischemia. The superior spatial resolution and volumetric acquisition of CCT has an important role in the diagnosis of other nonischemic causes of cardiomyopathies.

Original languageEnglish
Article number16
JournalCurrent Cardiovascular Imaging Reports
Issue number7
StatePublished - 1 Jul 2018
Externally publishedYes


  • CT perfusion
  • Cardiac CT
  • Cardiomyopathy
  • Dual-energy CT
  • Myocardial assessment


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