Nephrotoxicity associated with intravenous colistin (colistimethate sodium) treatment at a tertiary care medical center

Joshua D. Hartzell; Robert Neff; Julie Ake; Robin Howard; Stephen Olson; Kristopher Paolino; Mark Vishnepolsky; Amy Weintrob; Gienn Wortmann

doi:10.1086/599225

Nephrotoxicity associated with intravenous colistin (colistimethate sodium) treatment at a tertiary care medical center

Joshua D. Hartzell, Robert Neff, Julie Ake, Robin Howard, Stephen Olson, Kristopher Paolino, Mark Vishnepolsky, Amy Weintrob, Gienn Wortmann

Research output: Contribution to journal › Article › peer-review

300 Scopus citations

Abstract

The incidence of acute renal failure, defined by the risk, injury, or failure criteria of the RIFLE criteria (risk, injury, failure, loss, and end-stage kidney disease), in 66 patients who received colistimethate sodium was 45%, and 21% of patients stopped therapy because of nephrotoxicity. The RIFLE criteria should be used in the future to allow for comparison of nephrotoxicity among studies.

Original language	English
Pages (from-to)	1724-1728
Number of pages	5
Journal	Clinical Infectious Diseases
Volume	48
Issue number	12
DOIs	https://doi.org/10.1086/599225
State	Published - 15 Jun 2009
Externally published	Yes

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abstract = "The incidence of acute renal failure, defined by the risk, injury, or failure criteria of the RIFLE criteria (risk, injury, failure, loss, and end-stage kidney disease), in 66 patients who received colistimethate sodium was 45%, and 21% of patients stopped therapy because of nephrotoxicity. The RIFLE criteria should be used in the future to allow for comparison of nephrotoxicity among studies.",

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AU - Olson, Stephen

AU - Paolino, Kristopher

AU - Vishnepolsky, Mark

AU - Weintrob, Amy

AU - Wortmann, Gienn

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AB - The incidence of acute renal failure, defined by the risk, injury, or failure criteria of the RIFLE criteria (risk, injury, failure, loss, and end-stage kidney disease), in 66 patients who received colistimethate sodium was 45%, and 21% of patients stopped therapy because of nephrotoxicity. The RIFLE criteria should be used in the future to allow for comparison of nephrotoxicity among studies.

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Nephrotoxicity associated with intravenous colistin (colistimethate sodium) treatment at a tertiary care medical center

Abstract

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