New world monkey Aotus nancymae as a model for Campylobacter jejuni infection and immunity

Franca R. Jones; Shahida Baqar; Alfonso Gozalo; Gladys Nunez; Nereyda Espinoza; Sharina M. Reyes; Milagros Salazar; Rina Meza; Chad K. Porter; Stephen E. Walz

doi:10.1128/IAI.74.1.790-793.2006

New world monkey Aotus nancymae as a model for Campylobacter jejuni infection and immunity

Franca R. Jones^*
, Shahida Baqar
, Alfonso Gozalo
, Gladys Nunez
, Nereyda Espinoza
, Sharina M. Reyes
, Milagros Salazar
, Rina Meza
, Chad K. Porter
, Stephen E. Walz

^*Corresponding author for this work

Affiliated

Research output: Contribution to journal › Article › peer-review

38 Scopus citations

Abstract

Three groups of six monkeys (Aotus nancymae) each were inoculated intragastrically with increasing doses of Campylobacter jejuni. Infection resulted in fecal colonization (100% of monkeys), dose-related diarrhea, and robust immune responses. Colonization duration and diarrhea rate were reduced upon secondary challenge. A. nancymae may be useful for studying anti-Campylobacter vaccine efficacy.

Original language	English
Pages (from-to)	790-793
Number of pages	4
Journal	Infection and Immunity
Volume	74
Issue number	1
DOIs	https://doi.org/10.1128/IAI.74.1.790-793.2006
State	Published - Jan 2006

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title = "New world monkey Aotus nancymae as a model for Campylobacter jejuni infection and immunity",

abstract = "Three groups of six monkeys (Aotus nancymae) each were inoculated intragastrically with increasing doses of Campylobacter jejuni. Infection resulted in fecal colonization (100\% of monkeys), dose-related diarrhea, and robust immune responses. Colonization duration and diarrhea rate were reduced upon secondary challenge. A. nancymae may be useful for studying anti-Campylobacter vaccine efficacy.",

author = "Jones, \{Franca R.\} and Shahida Baqar and Alfonso Gozalo and Gladys Nunez and Nereyda Espinoza and Reyes, \{Sharina M.\} and Milagros Salazar and Rina Meza and Porter, \{Chad K.\} and Walz, \{Stephen E.\}",

year = "2006",

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AU - Jones, Franca R.

AU - Baqar, Shahida

AU - Gozalo, Alfonso

AU - Nunez, Gladys

AU - Espinoza, Nereyda

AU - Reyes, Sharina M.

AU - Salazar, Milagros

AU - Meza, Rina

AU - Porter, Chad K.

AU - Walz, Stephen E.

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AB - Three groups of six monkeys (Aotus nancymae) each were inoculated intragastrically with increasing doses of Campylobacter jejuni. Infection resulted in fecal colonization (100% of monkeys), dose-related diarrhea, and robust immune responses. Colonization duration and diarrhea rate were reduced upon secondary challenge. A. nancymae may be useful for studying anti-Campylobacter vaccine efficacy.

UR - https://www.scopus.com/pages/publications/29644447712

U2 - 10.1128/IAI.74.1.790-793.2006

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IS - 1

ER -

New world monkey Aotus nancymae as a model for Campylobacter jejuni infection and immunity

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