Nonalcoholic fatty liver disease: Clinical features, disease modifiers, and natural history

Dawn M. Torres, Stephen A. Harrison*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Scopus citations


Nonalcoholic fatty liver disease (NAFLD) typically presents as an asymptomatic elevation of liver-associated enzymes and has been associated with a number of clinical conditions that are included in the definition of the metabolic syndrome such as obesity, hyperlipidemia, and insulin resistance. NAFLD also has been shown to be related to a variety of conditions such as cardiovascular disease and obstructive sleep apnea. This review will address the clinical presentation and natural history of NAFLD as the hepatic manifestation of the metabolic syndrome.

Original languageEnglish
Title of host publicationAlcoholic and Non-Alcoholic Fatty Liver Disease
Subtitle of host publicationBench to Bedside
PublisherSpringer International Publishing
Number of pages12
ISBN (Electronic)9783319205380
ISBN (Print)9783319205373
StatePublished - 1 Jan 2015
Externally publishedYes


  • Diabetes mellitus
  • Natural history
  • Obesity
  • Obstructive sleep apnea
  • Steatohepatitis


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