TY - JOUR
T1 - North American Clinical Trials Network for Spinal Cord Injury Registry
T2 - Methodology and Analysis
AU - Toups, Elizabeth G.
AU - Ugiliweneza, Beatrice
AU - Howley, Susan P.
AU - Neal, Chris J.
AU - Harrop, James S.
AU - Guest, James D.
AU - Grossman, Robert G.
AU - Fehlings, Michael G.
N1 - Publisher Copyright:
© 2023 Mary Ann Liebert, Inc., publishers.
PY - 2023/9/1
Y1 - 2023/9/1
N2 - The North American Clinical Trials Network (NACTN) for Spinal Cord Injury (SCI) is a consortium of neurosurgery departments at university affiliated hospitals with medical, nursing, and rehabilitation personnel who are skilled in the assessment, evaluation, and management of SCI. NACTN was established with the goal of consistently advancing the quality of life of people with SCI through clinical trials of new therapies that provide robust evidence of safety and effectiveness. A prospective multi-center Registry was created to collect the natural course of the acute traumatic SCI patient from time of injury to 12 months follow-up. NACTN's network of hospitals enrolls a significant number of patients, defines and adheres to standard protocols, and provides the infrastructure and highly skilled personnel to conduct trials of therapy for SCI. Registry data have been used by academic institutions and by the biotechnology and pharmaceutical sectors to create comparison datasets for Phase I clinical trials of new therapies.
AB - The North American Clinical Trials Network (NACTN) for Spinal Cord Injury (SCI) is a consortium of neurosurgery departments at university affiliated hospitals with medical, nursing, and rehabilitation personnel who are skilled in the assessment, evaluation, and management of SCI. NACTN was established with the goal of consistently advancing the quality of life of people with SCI through clinical trials of new therapies that provide robust evidence of safety and effectiveness. A prospective multi-center Registry was created to collect the natural course of the acute traumatic SCI patient from time of injury to 12 months follow-up. NACTN's network of hospitals enrolls a significant number of patients, defines and adheres to standard protocols, and provides the infrastructure and highly skilled personnel to conduct trials of therapy for SCI. Registry data have been used by academic institutions and by the biotechnology and pharmaceutical sectors to create comparison datasets for Phase I clinical trials of new therapies.
KW - ASIA Impairment Score
KW - International Standards for Neurological Classification of Spinal Cord Injury
KW - data management
KW - registry
KW - spinal cord injury
UR - http://www.scopus.com/inward/record.url?scp=85169848587&partnerID=8YFLogxK
U2 - 10.1089/neu.2022.0403
DO - 10.1089/neu.2022.0403
M3 - Article
C2 - 37125443
AN - SCOPUS:85169848587
SN - 0897-7151
VL - 40
SP - 1817
EP - 1822
JO - Journal of Neurotrauma
JF - Journal of Neurotrauma
IS - 17-18
ER -