Obesity among HIV-infected persons: Impact of weight on CD4 cell count

Nancy F. Crum-Cianflone, Mollie Roediger, Lynn E. Eberly, Kurt Vyas, Mike L. Landrum, Anuradha Ganesan, Amy C. Weintrob, Robert Vincent Barthel, Brian K. Agan

Research output: Contribution to journalArticlepeer-review

54 Scopus citations


To assess the effect of obesity on CD4 cell counts, we estimated the association of time-updated BMI categories with CD4 changes among 1001 documented HIV seroconverters. During the pre-highly active antiretroviral therapy (HAART) era, a higher BMI was associated with less reduction in CD4 cell counts over time. However during the HAART era, obese versus normal weight patients had smaller increases in CD4 cell counts (+69 versus +116 cells, P = 0.01). Lower CD4 cell counts may now be another adverse consequence of obesity.

Original languageEnglish
Pages (from-to)1069-1072
Number of pages4
Issue number7
StatePublished - Apr 2010
Externally publishedYes


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