Obesity, inflammation and fibroids

Monica N. Modi; Charles Armstrong; William H. Catherino

Obesity, inflammation and fibroids

Monica N. Modi^*, Charles Armstrong, William H. Catherino

^*Corresponding author for this work

Gynecologic Surgery and Obstetrics

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

In the US, approximately 80% of African American women and 70% of white women will develop uterine fibroids by age 50. Based on the common racial predisposition for obesity and fibroids, significant effort has been directed to determine causality. The purpose of this chapter is to review the epidemiological and molecular studies that have found an association between obesity, inflammation and the development of uterine fibroids. Although this field is still emerging, results from studies in this area may lead to new therapies for fibroids directed at mediators of inflammation.

Original language	English
Title of host publication	Leiomyomas
Subtitle of host publication	Risk Factors, Clinical Manifestations and Treatment Options
Publisher	Nova Science Publishers, Inc.
Pages	31-43
Number of pages	13
ISBN (Electronic)	9781634636032
ISBN (Print)	9781634635844
State	Published - 1 Jan 2015

Cite this

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abstract = "In the US, approximately 80% of African American women and 70% of white women will develop uterine fibroids by age 50. Based on the common racial predisposition for obesity and fibroids, significant effort has been directed to determine causality. The purpose of this chapter is to review the epidemiological and molecular studies that have found an association between obesity, inflammation and the development of uterine fibroids. Although this field is still emerging, results from studies in this area may lead to new therapies for fibroids directed at mediators of inflammation.",

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N2 - In the US, approximately 80% of African American women and 70% of white women will develop uterine fibroids by age 50. Based on the common racial predisposition for obesity and fibroids, significant effort has been directed to determine causality. The purpose of this chapter is to review the epidemiological and molecular studies that have found an association between obesity, inflammation and the development of uterine fibroids. Although this field is still emerging, results from studies in this area may lead to new therapies for fibroids directed at mediators of inflammation.

AB - In the US, approximately 80% of African American women and 70% of white women will develop uterine fibroids by age 50. Based on the common racial predisposition for obesity and fibroids, significant effort has been directed to determine causality. The purpose of this chapter is to review the epidemiological and molecular studies that have found an association between obesity, inflammation and the development of uterine fibroids. Although this field is still emerging, results from studies in this area may lead to new therapies for fibroids directed at mediators of inflammation.

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