Opportunities for Enhanced Public Health Surveillance via Molecular Detection and Sequencing of Diverse Respiratory Viruses From Self-collected SARS-CoV-2 Antigen Test Swabs

Kat Schmidt*, Simon D. Pollett, Stephanie A. Richard, Vivian Hogan, Emily Hone, Jennifer Rothenberg, Rezalina Tant, Michele Wayman, Chantele Friend, Kamala Thapa, Lola Ulomi, Julian Davies, Amber Michel, Timothy H. Burgess, Robert J. O’Connell, Mark P. Simons, Drake H. Tilley, Anthony C. Fries, Rhonda E. Colombo*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

We sequenced and genotyped severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), influenza, adenovirus, and respiratory syncytial virus, among other pathogens, from residual anterior nasal swabs self-collected for rapid SARSCoV-2 antigen testing at the US Naval Academy. This is a key proof-of-concept for an acute respiratory infection surveillance approach, which could leverage prevalent SARS-CoV-2 antigen self-testing.

Original languageEnglish
Article numberofae447
JournalOpen Forum Infectious Diseases
Volume11
Issue number8
DOIs
StatePublished - 1 Aug 2024
Externally publishedYes

Keywords

  • SARS-CoV-2
  • human influenza
  • public health surveillance
  • respiratory tract infection
  • whole-genome sequencing

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