TY - JOUR
T1 - Pathema
T2 - A clade-specific bioinformatics resource center for pathogen research
AU - Brinkac, Lauren M.
AU - Davidsen, Tanja
AU - Beck, Erin
AU - Ganapathy, Anuradha
AU - Caler, Elisabet
AU - Dodson, Robert J.
AU - Durkin, A. Scott
AU - Harkins, Derek M.
AU - Lorenzi, Hernan
AU - Madupu, Ramana
AU - Sebastian, Yinong
AU - Shrivastava, Susmita
AU - Thiagarajan, Mathangi
AU - Orvis, Joshua
AU - Sundaram, Jaideep P.
AU - Crabtree, Jonathon
AU - Galens, Kevin
AU - Zhao, Yongmei
AU - Inman, Jason M.
AU - Montgomery, Robert
AU - Schobel, Seth
AU - Galinsky, Kevin
AU - Tanenbaum, David M.
AU - Resnick, Adam
AU - Zafar, Nikhat
AU - White, Owen
AU - Sutton, Granger
PY - 2009/10/20
Y1 - 2009/10/20
N2 - Pathema (http://pathema.jcvi.org) is one of the eight Bioinformatics Resource Centers (BRCs) funded by the National Institute of Allergy and Infectious Disease (NIAID) designed to serve as a core resource for the bio-defense and infectious disease research community. Pathema strives to support basic research and accelerate scientific progress for understanding, detecting, diagnosing and treating an established set of six target NIAID Category A-C pathogens: Category A priority pathogens; Bacillus anthracis and Clostridium botulinum, and Category B priority pathogens; Burkholderia mallei, Burkholderia pseudomallei, Clostridium perfringens and Entamoeba histolytica. Each target pathogen is represented in one of four distinct clade-specific Pathema web resources and underlying databases developed to target the specific data and analysis needs of each scientific community. All publicly available complete genome projects of phylogenetically related organisms are also represented, providing a comprehensive collection of organisms for comparative analyses. Pathema facilitates the scientific exploration of genomic and related data through its integration with web-based analysis tools, customized to obtain, display, and compute results relevant to ongoing pathogen research. Pathema serves the bio-defense and infectious disease research community by disseminating data resulting from pathogen genome sequencing projects and providing access to the results of inter-genomic comparisons for these organisms.
AB - Pathema (http://pathema.jcvi.org) is one of the eight Bioinformatics Resource Centers (BRCs) funded by the National Institute of Allergy and Infectious Disease (NIAID) designed to serve as a core resource for the bio-defense and infectious disease research community. Pathema strives to support basic research and accelerate scientific progress for understanding, detecting, diagnosing and treating an established set of six target NIAID Category A-C pathogens: Category A priority pathogens; Bacillus anthracis and Clostridium botulinum, and Category B priority pathogens; Burkholderia mallei, Burkholderia pseudomallei, Clostridium perfringens and Entamoeba histolytica. Each target pathogen is represented in one of four distinct clade-specific Pathema web resources and underlying databases developed to target the specific data and analysis needs of each scientific community. All publicly available complete genome projects of phylogenetically related organisms are also represented, providing a comprehensive collection of organisms for comparative analyses. Pathema facilitates the scientific exploration of genomic and related data through its integration with web-based analysis tools, customized to obtain, display, and compute results relevant to ongoing pathogen research. Pathema serves the bio-defense and infectious disease research community by disseminating data resulting from pathogen genome sequencing projects and providing access to the results of inter-genomic comparisons for these organisms.
UR - http://www.scopus.com/inward/record.url?scp=75549083527&partnerID=8YFLogxK
U2 - 10.1093/nar/gkp850
DO - 10.1093/nar/gkp850
M3 - Article
C2 - 19843611
AN - SCOPUS:75549083527
SN - 0305-1048
VL - 38
SP - D408-D414
JO - Nucleic Acids Research
JF - Nucleic Acids Research
IS - SUPPL.1
M1 - gkp850
ER -