Performance of the OraQuick rapid antibody test for diagnosis of human immunodeficiency virus type 1 infection in patients with various levels of exposure to highly active antiretroviral therapy

Robert J. O'Connell; Teresa M. Merritt; Jennifer A. Malia; Thomas C. VanCott; Matthew J. Dolan; Hassan Zahwa; William P. Bradley; Bernard M. Branson; Nelson L. Michael; Caroline C. De Witt

doi:10.1128/JCM.41.5.2153-2155.2003

Performance of the OraQuick rapid antibody test for diagnosis of human immunodeficiency virus type 1 infection in patients with various levels of exposure to highly active antiretroviral therapy

Robert J. O'Connell^*, Teresa M. Merritt, Jennifer A. Malia, Thomas C. VanCott, Matthew J. Dolan, Hassan Zahwa, William P. Bradley, Bernard M. Branson, Nelson L. Michael, Caroline C. De Witt

^*Corresponding author for this work

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95 Scopus citations

Abstract

With oral mucosal transudate and serum samples from 101 human immunodeficiency virus type 1 (HIV-1)-infected subjects and 100 HIV-1-negative volunteers, the OraQuick HIV-1 test demonstrated 100% specificity and 96% sensitivity. Four false-negative subjects, who were characterized by early initiation of effective antiretroviral therapy, demonstrated waning serum anti-gp41 titers and Western blot band intensities.

Original language	English
Pages (from-to)	2153-2155
Number of pages	3
Journal	Journal of Clinical Microbiology
Volume	41
Issue number	5
DOIs	https://doi.org/10.1128/JCM.41.5.2153-2155.2003
State	Published - 1 May 2003

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O'Connell, R. J., Merritt, T. M., Malia, J. A., VanCott, T. C., Dolan, M. J., Zahwa, H., Bradley, W. P., Branson, B. M., Michael, N. L., & De Witt, C. C. (2003). Performance of the OraQuick rapid antibody test for diagnosis of human immunodeficiency virus type 1 infection in patients with various levels of exposure to highly active antiretroviral therapy. Journal of Clinical Microbiology, 41(5), 2153-2155. https://doi.org/10.1128/JCM.41.5.2153-2155.2003

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title = "Performance of the OraQuick rapid antibody test for diagnosis of human immunodeficiency virus type 1 infection in patients with various levels of exposure to highly active antiretroviral therapy",

abstract = "With oral mucosal transudate and serum samples from 101 human immunodeficiency virus type 1 (HIV-1)-infected subjects and 100 HIV-1-negative volunteers, the OraQuick HIV-1 test demonstrated 100% specificity and 96% sensitivity. Four false-negative subjects, who were characterized by early initiation of effective antiretroviral therapy, demonstrated waning serum anti-gp41 titers and Western blot band intensities.",

author = "O'Connell, {Robert J.} and Merritt, {Teresa M.} and Malia, {Jennifer A.} and VanCott, {Thomas C.} and Dolan, {Matthew J.} and Hassan Zahwa and Bradley, {William P.} and Branson, {Bernard M.} and Michael, {Nelson L.} and {De Witt}, {Caroline C.}",

year = "2003",

month = may,

day = "1",

doi = "10.1128/JCM.41.5.2153-2155.2003",

language = "English",

volume = "41",

pages = "2153--2155",

journal = "Journal of Clinical Microbiology",

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publisher = "American Society for Microbiology 1752 N St., NW, Washington, DC",

number = "5",

}

O'Connell, RJ, Merritt, TM, Malia, JA, VanCott, TC, Dolan, MJ, Zahwa, H, Bradley, WP, Branson, BM, Michael, NL & De Witt, CC 2003, 'Performance of the OraQuick rapid antibody test for diagnosis of human immunodeficiency virus type 1 infection in patients with various levels of exposure to highly active antiretroviral therapy', Journal of Clinical Microbiology, vol. 41, no. 5, pp. 2153-2155. https://doi.org/10.1128/JCM.41.5.2153-2155.2003

Performance of the OraQuick rapid antibody test for diagnosis of human immunodeficiency virus type 1 infection in patients with various levels of exposure to highly active antiretroviral therapy. / O'Connell, Robert J.; Merritt, Teresa M.; Malia, Jennifer A. et al.
In: Journal of Clinical Microbiology, Vol. 41, No. 5, 01.05.2003, p. 2153-2155.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Performance of the OraQuick rapid antibody test for diagnosis of human immunodeficiency virus type 1 infection in patients with various levels of exposure to highly active antiretroviral therapy

AU - O'Connell, Robert J.

AU - Merritt, Teresa M.

AU - Malia, Jennifer A.

AU - VanCott, Thomas C.

AU - Dolan, Matthew J.

AU - Zahwa, Hassan

AU - Bradley, William P.

AU - Branson, Bernard M.

AU - Michael, Nelson L.

AU - De Witt, Caroline C.

PY - 2003/5/1

Y1 - 2003/5/1

N2 - With oral mucosal transudate and serum samples from 101 human immunodeficiency virus type 1 (HIV-1)-infected subjects and 100 HIV-1-negative volunteers, the OraQuick HIV-1 test demonstrated 100% specificity and 96% sensitivity. Four false-negative subjects, who were characterized by early initiation of effective antiretroviral therapy, demonstrated waning serum anti-gp41 titers and Western blot band intensities.

AB - With oral mucosal transudate and serum samples from 101 human immunodeficiency virus type 1 (HIV-1)-infected subjects and 100 HIV-1-negative volunteers, the OraQuick HIV-1 test demonstrated 100% specificity and 96% sensitivity. Four false-negative subjects, who were characterized by early initiation of effective antiretroviral therapy, demonstrated waning serum anti-gp41 titers and Western blot band intensities.

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DO - 10.1128/JCM.41.5.2153-2155.2003

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SN - 0095-1137

VL - 41

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JO - Journal of Clinical Microbiology

JF - Journal of Clinical Microbiology

IS - 5

ER -

Performance of the OraQuick rapid antibody test for diagnosis of human immunodeficiency virus type 1 infection in patients with various levels of exposure to highly active antiretroviral therapy

Abstract

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