Peripheral Neuropathy and Nerve Compression Syndromes in Burns

Amy L. Strong, Shailesh Agarwal, Paul S. Cederna, Benjamin Levi*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

26 Scopus citations


Peripheral neuropathy and nerve compression syndromes lead to substantial morbidity following burn injury. Patients present with pain, paresthesias, or weakness along a specific nerve distribution or experience generalized peripheral neuropathy. The symptoms manifest at various times from within one week of hospitalization to many months after wound closure. Peripheral neuropathy may be caused by vascular occlusion of vasa nervorum, inflammation, neurotoxin production leading to apoptosis, and direct destruction of nerves from the burn injury. This article discusses the natural history, diagnosis, current treatments, and future directions for potential interventions for peripheral neuropathy and nerve compression syndromes related to burn injury.

Original languageEnglish
Pages (from-to)793-803
Number of pages11
JournalClinics in Plastic Surgery
Issue number4
StatePublished - Oct 2017
Externally publishedYes


  • Nerve compression syndromes
  • Peripheral nerves
  • Peripheral neuropathy


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