TY - JOUR
T1 - Physical activity
T2 - An essential component of lifestyle modification in NAFLD
AU - Rodriguez, Benjamin
AU - Torres, Dawn M.
AU - Harrison, Stephen A.
PY - 2012/12
Y1 - 2012/12
N2 - NAFLD encompasses a spectrum of liver diseases pertaining to fat accumulation in the liver in the absence of significant alcohol consumption. NASH is the most clinically relevant subset of NAFLD, and patients with NASH have an increased risk of progression to cirrhosis or developing liver cancer. No pharmacotherapy is currently approved for NAFLD, and lifestyle modification via diet and exercise is most commonly recommended. The optimal physical activity regimen in terms of both effectiveness and compliance remains to be determined and is the focus of this Review.
AB - NAFLD encompasses a spectrum of liver diseases pertaining to fat accumulation in the liver in the absence of significant alcohol consumption. NASH is the most clinically relevant subset of NAFLD, and patients with NASH have an increased risk of progression to cirrhosis or developing liver cancer. No pharmacotherapy is currently approved for NAFLD, and lifestyle modification via diet and exercise is most commonly recommended. The optimal physical activity regimen in terms of both effectiveness and compliance remains to be determined and is the focus of this Review.
UR - http://www.scopus.com/inward/record.url?scp=84870591332&partnerID=8YFLogxK
U2 - 10.1038/nrgastro.2012.200
DO - 10.1038/nrgastro.2012.200
M3 - Review article
C2 - 23090329
AN - SCOPUS:84870591332
SN - 1759-5045
VL - 9
SP - 726
EP - 731
JO - Nature Reviews Gastroenterology and Hepatology
JF - Nature Reviews Gastroenterology and Hepatology
IS - 12
ER -