Posttreatment changes in Escherichia coli antimicrobial susceptibility rates among diarrheic patients treated with ciprofloxacin

Shannon D. Putnam, John W. Sanders, David R. Tribble, David R. Rockabrand, Mark S. Riddle, Patrick J. Rozmajzl, Robert W. Frenck

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Changes in antimicrobial resistance of Escherichia coli among deployed U.S. military personnel being treated for diarrhea were evaluated. Stool samples were collected pretreatment and on days 7, 14, and 28 posttreatment. Resistance to ciprofloxacin was noted in 13.3% of baseline specimens, and rates of resistance against multiple antibiotics increased dramatically from baseline to day 7 and then tapered off to return to pretreatment levels by day 28, except for ciprofloxacin, suggesting that population accumulative usage of fluoroquinolones may result in an incremental increase in resistance rates.

Original languageEnglish
Pages (from-to)2571-2572
Number of pages2
JournalAntimicrobial Agents and Chemotherapy
Volume49
Issue number6
DOIs
StatePublished - Jun 2005

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