Precision medicine applications in prostate cancer

Edel M. McCrea; Daniel K. Lee; Tristan M. Sissung; William D. Figg

doi:10.1177/1758835918776920

Precision medicine applications in prostate cancer

Edel M. McCrea, Daniel K. Lee, Tristan M. Sissung, William D. Figg^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

9 Scopus citations

Abstract

Aided by developments in diagnostics and therapeutics, healthcare is increasingly moving toward precision medicine, in which treatment is customized to each individual. We discuss the relevance of precision medicine in prostate cancer, including gene targets, therapeutics and resistance mechanisms. We foresee precision medicine becoming an integral component of prostate cancer management to increase response to therapy and prolong survival.

Original language	English
Journal	Therapeutic Advances in Medical Oncology
Volume	10
DOIs	https://doi.org/10.1177/1758835918776920
State	Published - 1 Jan 2018
Externally published	Yes

Keywords

AR-V7
androgen deprivation therapy resistance
microsatellite instability
organic anion transporting polypeptide 1B3
precision medicine
sex determining region Y box2

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10.1177/1758835918776920

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abstract = "Aided by developments in diagnostics and therapeutics, healthcare is increasingly moving toward precision medicine, in which treatment is customized to each individual. We discuss the relevance of precision medicine in prostate cancer, including gene targets, therapeutics and resistance mechanisms. We foresee precision medicine becoming an integral component of prostate cancer management to increase response to therapy and prolong survival.",

keywords = "AR-V7, androgen deprivation therapy resistance, microsatellite instability, organic anion transporting polypeptide 1B3, precision medicine, sex determining region Y box2",

author = "McCrea, {Edel M.} and Lee, {Daniel K.} and Sissung, {Tristan M.} and Figg, {William D.}",

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AU - McCrea, Edel M.

AU - Lee, Daniel K.

AU - Sissung, Tristan M.

AU - Figg, William D.

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PY - 2018/1/1

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AB - Aided by developments in diagnostics and therapeutics, healthcare is increasingly moving toward precision medicine, in which treatment is customized to each individual. We discuss the relevance of precision medicine in prostate cancer, including gene targets, therapeutics and resistance mechanisms. We foresee precision medicine becoming an integral component of prostate cancer management to increase response to therapy and prolong survival.

KW - AR-V7

KW - androgen deprivation therapy resistance

KW - microsatellite instability

KW - organic anion transporting polypeptide 1B3

KW - precision medicine

KW - sex determining region Y box2

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JO - Therapeutic Advances in Medical Oncology

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Precision medicine applications in prostate cancer

Abstract

Keywords

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