@article{b729b06271594d5bb8cf4d2ebaee141e,
title = "Precision medicine applications in prostate cancer",
abstract = "Aided by developments in diagnostics and therapeutics, healthcare is increasingly moving toward precision medicine, in which treatment is customized to each individual. We discuss the relevance of precision medicine in prostate cancer, including gene targets, therapeutics and resistance mechanisms. We foresee precision medicine becoming an integral component of prostate cancer management to increase response to therapy and prolong survival.",
keywords = "AR-V7, androgen deprivation therapy resistance, microsatellite instability, organic anion transporting polypeptide 1B3, precision medicine, sex determining region Y box2",
author = "McCrea, {Edel M.} and Lee, {Daniel K.} and Sissung, {Tristan M.} and Figg, {William D.}",
note = "Funding Information: Correspondence to: William D. Figg Clinical Pharmacology Program, Office of the Clinical Director, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Rockville Pike, Bldg 10/Room 5A01, Bethesda, MD 20892, USA figgw@mail.nih.gov Edel M. McCrea Molecular Pharmacology Section, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA Daniel K. Lee Medical Oncology Service, and the Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA Tristan M. Sissung Clinical Pharmacology Program, Office of the Clinical Director, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA Funding Information: Edel M. McCrea and Daniel K. Lee are joint first authors. This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors. Publisher Copyright: {\textcopyright} The Author(s), 2018.",
year = "2018",
month = jan,
day = "1",
doi = "10.1177/1758835918776920",
language = "English",
volume = "10",
journal = "Therapeutic Advances in Medical Oncology",
issn = "1758-8340",
}