Precision Medicine Applications to Manage Multiply Injured Patients With Orthopaedic Trauma

Todd O. McKinley*, Felipe A. Lisboa, Annamarie D. Horan, Greg E. Gaski, Samir Mehta

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


Precision medicine offers potential for improved outcomes by tailoring interventions based on patient-specific demographics and disease-specific data. Precision methods are relatively unexplored in trauma patients. New research is being looked at for precision methods to treat patients with large extremity wounds, nonunions, and fractures associated with polytrauma. Precision-based clinical decision tools are being validated to optimize timing for open wound definitive closure. Early patient-specific biomarkers to stratify nonunion risk within 1 week of fracture are being explored. Patient-specific data to stage timing of major fracture interventions in multiply injured patients are being interrogated.

Original languageEnglish
Pages (from-to)S25-S29
JournalJournal of Orthopaedic Trauma
StatePublished - 1 Jun 2019
Externally publishedYes


  • Multiply injured patient
  • Nonunion
  • Precision medicine
  • Wound infection


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