Preemptive Tecovirimat Use in an Active Duty Service Member Who Presented with Acute Myeloid Leukemia after Smallpox Vaccination

David A. Lindholm; Raymond D. Fisher; Jay R. Montgomery; Whitni Davidson; Patricia A. Yu; Yon C. Yu; Jillybeth Burgado; Kimberly Wilkins; Brett W. Petersen; Jason F. Okulicz

doi:10.1093/cid/ciz286

Preemptive Tecovirimat Use in an Active Duty Service Member Who Presented with Acute Myeloid Leukemia after Smallpox Vaccination

David A. Lindholm^*, Raymond D. Fisher, Jay R. Montgomery, Whitni Davidson, Patricia A. Yu, Yon C. Yu, Jillybeth Burgado, Kimberly Wilkins, Brett W. Petersen, Jason F. Okulicz

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

Smallpox vaccine is contraindicated in immunosuppression due to increased risk for adverse reactions (eg, progressive vaccinia). We describe the first-ever use of tecovirimat as a preemptive vaccinia virus treatment strategy during induction chemotherapy in an active duty service member who presented with acute leukemia and inadvertent autoinoculation after smallpox vaccination.

Original language	English
Pages (from-to)	2205-2207
Number of pages	3
Journal	Clinical Infectious Diseases
Volume	69
Issue number	12
DOIs	https://doi.org/10.1093/cid/ciz286
State	Published - 27 Nov 2019
Externally published	Yes

Keywords

ST-246
leukemia
smallpox vaccine
tecovirimat
vaccinia

Access to Document

10.1093/cid/ciz286

Cite this

@article{9ea15696bab34733ba858c26f61b5c97,

title = "Preemptive Tecovirimat Use in an Active Duty Service Member Who Presented with Acute Myeloid Leukemia after Smallpox Vaccination",

abstract = "Smallpox vaccine is contraindicated in immunosuppression due to increased risk for adverse reactions (eg, progressive vaccinia). We describe the first-ever use of tecovirimat as a preemptive vaccinia virus treatment strategy during induction chemotherapy in an active duty service member who presented with acute leukemia and inadvertent autoinoculation after smallpox vaccination.",

keywords = "ST-246, leukemia, smallpox vaccine, tecovirimat, vaccinia",

author = "Lindholm, {David A.} and Fisher, {Raymond D.} and Montgomery, {Jay R.} and Whitni Davidson and Yu, {Patricia A.} and Yu, {Yon C.} and Jillybeth Burgado and Kimberly Wilkins and Petersen, {Brett W.} and Okulicz, {Jason F.}",

note = "Publisher Copyright: {\textcopyright} 2019 The Author(s).",

year = "2019",

month = nov,

day = "27",

doi = "10.1093/cid/ciz286",

language = "English",

volume = "69",

pages = "2205--2207",

journal = "Clinical Infectious Diseases",

issn = "1058-4838",

publisher = "Oxford University Press",

number = "12",

}

TY - JOUR

T1 - Preemptive Tecovirimat Use in an Active Duty Service Member Who Presented with Acute Myeloid Leukemia after Smallpox Vaccination

AU - Lindholm, David A.

AU - Fisher, Raymond D.

AU - Montgomery, Jay R.

AU - Davidson, Whitni

AU - Yu, Patricia A.

AU - Yu, Yon C.

AU - Burgado, Jillybeth

AU - Wilkins, Kimberly

AU - Petersen, Brett W.

AU - Okulicz, Jason F.

PY - 2019/11/27

Y1 - 2019/11/27

N2 - Smallpox vaccine is contraindicated in immunosuppression due to increased risk for adverse reactions (eg, progressive vaccinia). We describe the first-ever use of tecovirimat as a preemptive vaccinia virus treatment strategy during induction chemotherapy in an active duty service member who presented with acute leukemia and inadvertent autoinoculation after smallpox vaccination.

AB - Smallpox vaccine is contraindicated in immunosuppression due to increased risk for adverse reactions (eg, progressive vaccinia). We describe the first-ever use of tecovirimat as a preemptive vaccinia virus treatment strategy during induction chemotherapy in an active duty service member who presented with acute leukemia and inadvertent autoinoculation after smallpox vaccination.

KW - ST-246

KW - leukemia

KW - smallpox vaccine

KW - tecovirimat

KW - vaccinia

UR - http://www.scopus.com/inward/record.url?scp=85075805510&partnerID=8YFLogxK

U2 - 10.1093/cid/ciz286

DO - 10.1093/cid/ciz286

M3 - Article

C2 - 30959520

AN - SCOPUS:85075805510

SN - 1058-4838

VL - 69

SP - 2205

EP - 2207

JO - Clinical Infectious Diseases

JF - Clinical Infectious Diseases

IS - 12

ER -

Preemptive Tecovirimat Use in an Active Duty Service Member Who Presented with Acute Myeloid Leukemia after Smallpox Vaccination

Abstract

Keywords

Access to Document

Fingerprint

Cite this