Preparing better: Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) therapeutics trials lessons learned: A call to the future

Stacey J. Adam; Timothy G. Buchman; Judith S. Currier; Ruxandra Draghia-Akli; Josh P. Fessel; Elizabeth S. Higgs; Eric A. Hughes; Lisa Lavange; Joseph P. Menetski; Sarah W. Read; Yves Rosenberg; Randall Tressler

doi:10.1017/cts.2024.178

Preparing better: Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) therapeutics trials lessons learned: A call to the future

Stacey J. Adam^*, Timothy G. Buchman, Judith S. Currier, Ruxandra Draghia-Akli, Josh P. Fessel, Elizabeth S. Higgs, Eric A. Hughes, Lisa Lavange, Joseph P. Menetski, Sarah W. Read, Yves Rosenberg, Randall Tressler

^*Corresponding author for this work

Surgery

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Abstract

The Accelerating COVID-19 Therapeutic Interventions and Vaccines Therapeutic-Clinical Working Group members gathered critical recommendations in follow-up to lessons learned manuscripts released earlier in the COVID-19 pandemic. Lessons around agent prioritization, preclinical therapeutics testing, master protocol design and implementation, drug manufacturing and supply, data sharing, and public-private partnership value are shared to inform responses to future pandemics.

Original language	English
Article number	e150
Journal	Journal of Clinical and Translational Science
Volume	8
Issue number	1
DOIs	https://doi.org/10.1017/cts.2024.178
State	Published - 15 Oct 2024

Keywords

Covid-19
lessons learned
master protocol
therapeutics
trials

Access to Document

10.1017/cts.2024.178

Cite this

Adam, S. J., Buchman, T. G., Currier, J. S., Draghia-Akli, R., Fessel, J. P., Higgs, E. S., Hughes, E. A., Lavange, L., Menetski, J. P., Read, S. W., Rosenberg, Y., & Tressler, R. (2024). Preparing better: Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) therapeutics trials lessons learned: A call to the future. Journal of Clinical and Translational Science, 8(1), Article e150. https://doi.org/10.1017/cts.2024.178

@article{e64906b5fc834c039de2805734f54878,

title = "Preparing better: Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) therapeutics trials lessons learned: A call to the future",

abstract = "The Accelerating COVID-19 Therapeutic Interventions and Vaccines Therapeutic-Clinical Working Group members gathered critical recommendations in follow-up to lessons learned manuscripts released earlier in the COVID-19 pandemic. Lessons around agent prioritization, preclinical therapeutics testing, master protocol design and implementation, drug manufacturing and supply, data sharing, and public-private partnership value are shared to inform responses to future pandemics.",

keywords = "Covid-19, lessons learned, master protocol, therapeutics, trials",

author = "Adam, {Stacey J.} and Buchman, {Timothy G.} and Currier, {Judith S.} and Ruxandra Draghia-Akli and Fessel, {Josh P.} and Higgs, {Elizabeth S.} and Hughes, {Eric A.} and Lisa Lavange and Menetski, {Joseph P.} and Read, {Sarah W.} and Yves Rosenberg and Randall Tressler",

note = "Publisher Copyright: {\textcopyright} National Institutes of Health and the Author(s), 2024.",

year = "2024",

month = oct,

day = "15",

doi = "10.1017/cts.2024.178",

language = "English",

volume = "8",

journal = "Journal of Clinical and Translational Science",

issn = "2059-8661",

number = "1",

}

Adam, SJ, Buchman, TG, Currier, JS, Draghia-Akli, R, Fessel, JP, Higgs, ES, Hughes, EA, Lavange, L, Menetski, JP, Read, SW, Rosenberg, Y & Tressler, R 2024, 'Preparing better: Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) therapeutics trials lessons learned: A call to the future', Journal of Clinical and Translational Science, vol. 8, no. 1, e150. https://doi.org/10.1017/cts.2024.178

Preparing better: Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) therapeutics trials lessons learned: A call to the future. / Adam, Stacey J.; Buchman, Timothy G.; Currier, Judith S. et al.
In: Journal of Clinical and Translational Science, Vol. 8, No. 1, e150, 15.10.2024.

Research output: Contribution to journal › Review article › peer-review

TY - JOUR

T1 - Preparing better

T2 - Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) therapeutics trials lessons learned: A call to the future

AU - Adam, Stacey J.

AU - Buchman, Timothy G.

AU - Currier, Judith S.

AU - Draghia-Akli, Ruxandra

AU - Fessel, Josh P.

AU - Higgs, Elizabeth S.

AU - Hughes, Eric A.

AU - Lavange, Lisa

AU - Menetski, Joseph P.

AU - Read, Sarah W.

AU - Rosenberg, Yves

AU - Tressler, Randall

PY - 2024/10/15

Y1 - 2024/10/15

N2 - The Accelerating COVID-19 Therapeutic Interventions and Vaccines Therapeutic-Clinical Working Group members gathered critical recommendations in follow-up to lessons learned manuscripts released earlier in the COVID-19 pandemic. Lessons around agent prioritization, preclinical therapeutics testing, master protocol design and implementation, drug manufacturing and supply, data sharing, and public-private partnership value are shared to inform responses to future pandemics.

AB - The Accelerating COVID-19 Therapeutic Interventions and Vaccines Therapeutic-Clinical Working Group members gathered critical recommendations in follow-up to lessons learned manuscripts released earlier in the COVID-19 pandemic. Lessons around agent prioritization, preclinical therapeutics testing, master protocol design and implementation, drug manufacturing and supply, data sharing, and public-private partnership value are shared to inform responses to future pandemics.

KW - Covid-19

KW - lessons learned

KW - master protocol

KW - therapeutics

KW - trials

UR - http://www.scopus.com/inward/record.url?scp=85208274454&partnerID=8YFLogxK

U2 - 10.1017/cts.2024.178

DO - 10.1017/cts.2024.178

M3 - Review article

AN - SCOPUS:85208274454

SN - 2059-8661

VL - 8

JO - Journal of Clinical and Translational Science

JF - Journal of Clinical and Translational Science

IS - 1

M1 - e150

ER -