Preventing HIV-1 Transmission Through Vaccine-Induced Immune Responses

Jean Louis Excler, Merlin Robb, Jerome H. Kim, Nelson L. Michael

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

According to UNAIDS, globally 35.0 million people were living with HIV at the end of 2013. Sub-Saharan Africa remains most severely affected, accounting for 71% of the people living with HIV-1 worldwide. The number of people newly infected or who died from AIDS-related causes declined worldwide. Despite genuine, although unequal and fragile, successes in prevention programs attributed to strengthening and scaling up prevention strategies and antiretroviral treatment, the development of a preventive HIV-1 vaccine as part of a comprehensive prevention package remains among the best hopes for controlling the HIV-1 pandemic. By inducing appropriate immune responses directed against a specific pathogen, vaccines remain the most powerful public health tool to prevent infectious diseases.

Original languageEnglish
Title of host publicationEncyclopedia of AIDS
PublisherSpringer New York
Pages1690-1698
Number of pages9
ISBN (Electronic)9781493971015
ISBN (Print)9781493971008
StatePublished - 1 Jan 2018

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