Protein microarrays: Meeting analytical challenges for clinical applications

Lance A. Liotta*, Virginia Espina, Arpita I. Mehta, Valerie Calvert, Kevin Rosenblatt, David Geho, Peter J. Munson, Lynn Young, Julia Wulfkuhle, Emanuel F. Petricoin

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

399 Scopus citations

Abstract

Protein microarrays, one emerging class of proteomic technologies, have broad applications for discovery and quantitative analysis. A rapidly expanding use of this technology is the acquisition of information about the posttranslational modifications of proteins reflecting the activity state of signal pathways and networks, and is now employed for the analysis of biopsy samples in clinical trial research.

Original languageEnglish
Pages (from-to)317-325
Number of pages9
JournalCancer Cell
Volume3
Issue number4
DOIs
StatePublished - Apr 2003
Externally publishedYes

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