Protein microarrays: Meeting analytical challenges for clinical applications

Lance A. Liotta; Virginia Espina; Arpita I. Mehta; Valerie Calvert; Kevin Rosenblatt; David Geho; Peter J. Munson; Lynn Young; Julia Wulfkuhle; Emanuel F. Petricoin

doi:10.1016/S1535-6108(03)00086-2

Protein microarrays: Meeting analytical challenges for clinical applications

Lance A. Liotta^*, Virginia Espina, Arpita I. Mehta, Valerie Calvert, Kevin Rosenblatt, David Geho, Peter J. Munson, Lynn Young, Julia Wulfkuhle, Emanuel F. Petricoin

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

400 Scopus citations

Abstract

Protein microarrays, one emerging class of proteomic technologies, have broad applications for discovery and quantitative analysis. A rapidly expanding use of this technology is the acquisition of information about the posttranslational modifications of proteins reflecting the activity state of signal pathways and networks, and is now employed for the analysis of biopsy samples in clinical trial research.

Original language	English
Pages (from-to)	317-325
Number of pages	9
Journal	Cancer Cell
Volume	3
Issue number	4
DOIs	https://doi.org/10.1016/S1535-6108(03)00086-2
State	Published - Apr 2003
Externally published	Yes

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title = "Protein microarrays: Meeting analytical challenges for clinical applications",

abstract = "Protein microarrays, one emerging class of proteomic technologies, have broad applications for discovery and quantitative analysis. A rapidly expanding use of this technology is the acquisition of information about the posttranslational modifications of proteins reflecting the activity state of signal pathways and networks, and is now employed for the analysis of biopsy samples in clinical trial research.",

author = "Liotta, {Lance A.} and Virginia Espina and Mehta, {Arpita I.} and Valerie Calvert and Kevin Rosenblatt and David Geho and Munson, {Peter J.} and Lynn Young and Julia Wulfkuhle and Petricoin, {Emanuel F.}",

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AU - Liotta, Lance A.

AU - Espina, Virginia

AU - Mehta, Arpita I.

AU - Calvert, Valerie

AU - Rosenblatt, Kevin

AU - Geho, David

AU - Munson, Peter J.

AU - Young, Lynn

AU - Wulfkuhle, Julia

AU - Petricoin, Emanuel F.

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AB - Protein microarrays, one emerging class of proteomic technologies, have broad applications for discovery and quantitative analysis. A rapidly expanding use of this technology is the acquisition of information about the posttranslational modifications of proteins reflecting the activity state of signal pathways and networks, and is now employed for the analysis of biopsy samples in clinical trial research.

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DO - 10.1016/S1535-6108(03)00086-2

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SN - 1535-6108

VL - 3

SP - 317

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Protein microarrays: Meeting analytical challenges for clinical applications

Abstract

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