Proteomic applications for the early detection of cancer

Julia D. Wulfkuhle, Lance A. Liotta, Emanuel F. Petricoin*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

793 Scopus citations

Abstract

The ability of physicians to effectively treat and cure cancer is directly dependent on their ability to detect cancers at their earliest stages. Proteomic analyses of early-stage cancers have provided new insights into the changes that occur in the early phases of tumorigenesis and represent a new resource of candidate biomarkers for early-stage disease. Studies that profile proteomic patterns in body fluids also present new opportunities for the development of novel, highly sensitive diagnostic tools for the early detection of cancer.

Original languageEnglish
Pages (from-to)267-275
Number of pages9
JournalNature Reviews Cancer
Volume3
Issue number4
DOIs
StatePublished - Apr 2003
Externally publishedYes

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