Proteomics approaches to biomarker detection

Ming Zhou, Thomas P. Conrads, Timothy D. Veenstra*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

28 Scopus citations


The development of mass spectrometry (MS) technologies has brought the ability to gather massive amounts of data characterising the proteomes of complex mixtures. A major focus in proteomics is to leverage this data-gathering capability to conduct comparative analyses of biofluids from healthy and disease-affected patients for the identification of highly specific biomarkers and/or the development of MS-based diagnostic platforms. Much effort has gone into optimising the biofluid proteome coverage that can be obtained using these technologies, leaving proteomics poised to make an important impact in disease diagnostics in the future.

Original languageEnglish
Pages (from-to)69-75
Number of pages7
JournalBriefings in Functional Genomics and Proteomics
Issue number1
StatePublished - May 2005
Externally publishedYes


  • Biomarkers
  • Mass spectrometry
  • Proteomics
  • Serum


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