Pulmonary hemorrhage syndrome associated with an autochthonous case of dengue hemorrhagic fever

Robert F. Setlik*, Daniel Ouellette, Julia Morgan, C. Kenneth McAllister, David Dorsey, Brian K. Agan, Lynn Horvath, Michelle K. Zimmerman, Bret Purcell

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

31 Scopus citations


Dengue fever is a major public health problem worldwide. Dengue hemorrhagic fever, a much rarer form of the disease, occurs when a person previously infected with dengue is re-infected with a different viral serotype. In recent years the infection rates of dengue and both clinical syndromes have increased along the United States-Mexico border. We present the case of a 61-year-old Laotian female who presented with a 1-week history of fever, altered mental status, oral ulceration, and rash. The patient developed diffuse pulmonary hemorrhage and anemia requiring multiple transfusions. She eventually sustained multi-organ system failure and expired. Both the titer data and serologies were consistent with the diagnosis of dengue hemorrhagic fever. We hypothesize that this syndrome was the result of re-infection occurring within the United States. This case is also unusual in that it is the second reported in the literature of pulmonary hemorrhages associated with dengue hemorrhagic fever.

Original languageEnglish
Pages (from-to)688-691
Number of pages4
JournalSouthern Medical Journal
Issue number7
StatePublished - Jul 2004


  • Dengue hemorrhagic fever
  • Hemoptysis
  • Pulmonary hemorrhage


Dive into the research topics of 'Pulmonary hemorrhage syndrome associated with an autochthonous case of dengue hemorrhagic fever'. Together they form a unique fingerprint.

Cite this