Quality of Life Impact of Cochlear Implantation for Single-Sided Deafness: Assessing the Interrelationship of Objective and Subjective Measures

Anthony M Tolisano; Elicia M Pillion; Coral E Dirks; Matthew T Ryan; Joshua G W Bernstein

doi:10.1097/MAO.0000000000003783

Quality of Life Impact of Cochlear Implantation for Single-Sided Deafness: Assessing the Interrelationship of Objective and Subjective Measures

Anthony M Tolisano, Elicia M Pillion, Coral E Dirks, Matthew T Ryan, Joshua G W Bernstein

Uniformed Services University of the Health Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

OBJECTIVE: To determine the effect on quality of life (QOL) of cochlear implantation (CI) for single-sided deafness (SSD) and asymmetric hearing loss (AHL) using the first psychometrically developed CI-specific QOL tool for English-speaking patients and to assess its relationship to objective perceptual measures.

STUDY DESIGN: Retrospective cohort study.

SETTING: Tertiary-care medical center.

PATIENTS: English-speaking adults with SSD or AHL.

INTERVENTIONS: Unilateral CI.

MAIN OUTCOME MEASURES: Cochlear Implant Quality of Life (CIQOL) score, CI-alone speech-in-quiet (SIQ) score (CNC and AzBio), binaural speech-in-noise (SIN) threshold, binaural azimuthal sound localization (SL) error.

RESULTS: At the most recent postoperative evaluation (median, 9.3 months postimplantation), 25 of 28 subjects (89%) had a CIQOL improvement, with the improvement considered clinically beneficial (>3 points) for 18 of 28 subjects (64%). Group-mean CIQOL improvement was observed at the first postoperative visit and did not change significantly thereafter. Objective perceptual measures (SL, SIQ, SIN) continued to improve over 12 months after implantation. Linear mixed-model regression analyses showed a moderate positive correlation between SIN and SIQ improvements (r = 0.50 to 0.59, p < 0.0001) and a strong positive correlation between the improvement in the two SIQ measures (r = 0.89, p < 0.0001). No significant relationships were observed ( p > 0.05) among QOL or the objective perceptual measures.

CONCLUSIONS: QOL improved for the majority of subjects implanted for SSD and AHL. Different time courses for improvement in QOL and audiologic tests, combined with the lack of significant relationships among them, suggest that QOL outcomes reflect different aspects of the CI experience than those captured by speech-understanding and localization measures. SIQ may substitute for SIN when clinical constraints exist.

Original language	English
Pages (from-to)	e125-e132
Journal	Otology and Neurotology
Volume	44
Issue number	3
DOIs	https://doi.org/10.1097/MAO.0000000000003783
State	Published - 1 Mar 2023

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@article{6028d168c4cb4b739640be3d7e8ee9aa,

title = "Quality of Life Impact of Cochlear Implantation for Single-Sided Deafness: Assessing the Interrelationship of Objective and Subjective Measures",

abstract = "OBJECTIVE: To determine the effect on quality of life (QOL) of cochlear implantation (CI) for single-sided deafness (SSD) and asymmetric hearing loss (AHL) using the first psychometrically developed CI-specific QOL tool for English-speaking patients and to assess its relationship to objective perceptual measures.STUDY DESIGN: Retrospective cohort study.SETTING: Tertiary-care medical center.PATIENTS: English-speaking adults with SSD or AHL.INTERVENTIONS: Unilateral CI.MAIN OUTCOME MEASURES: Cochlear Implant Quality of Life (CIQOL) score, CI-alone speech-in-quiet (SIQ) score (CNC and AzBio), binaural speech-in-noise (SIN) threshold, binaural azimuthal sound localization (SL) error.RESULTS: At the most recent postoperative evaluation (median, 9.3 months postimplantation), 25 of 28 subjects (89%) had a CIQOL improvement, with the improvement considered clinically beneficial (>3 points) for 18 of 28 subjects (64%). Group-mean CIQOL improvement was observed at the first postoperative visit and did not change significantly thereafter. Objective perceptual measures (SL, SIQ, SIN) continued to improve over 12 months after implantation. Linear mixed-model regression analyses showed a moderate positive correlation between SIN and SIQ improvements (r = 0.50 to 0.59, p < 0.0001) and a strong positive correlation between the improvement in the two SIQ measures (r = 0.89, p < 0.0001). No significant relationships were observed ( p > 0.05) among QOL or the objective perceptual measures.CONCLUSIONS: QOL improved for the majority of subjects implanted for SSD and AHL. Different time courses for improvement in QOL and audiologic tests, combined with the lack of significant relationships among them, suggest that QOL outcomes reflect different aspects of the CI experience than those captured by speech-understanding and localization measures. SIQ may substitute for SIN when clinical constraints exist.",

author = "Tolisano, {Anthony M} and Pillion, {Elicia M} and Dirks, {Coral E} and Ryan, {Matthew T} and Bernstein, {Joshua G W}",

note = "Copyright {\textcopyright} 2022, Otology & Neurotology, Inc.",

year = "2023",

month = mar,

day = "1",

doi = "10.1097/MAO.0000000000003783",

language = "English",

volume = "44",

pages = "e125--e132",

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TY - JOUR

T1 - Quality of Life Impact of Cochlear Implantation for Single-Sided Deafness

T2 - Assessing the Interrelationship of Objective and Subjective Measures

AU - Tolisano, Anthony M

AU - Pillion, Elicia M

AU - Dirks, Coral E

AU - Ryan, Matthew T

AU - Bernstein, Joshua G W

PY - 2023/3/1

Y1 - 2023/3/1

N2 - OBJECTIVE: To determine the effect on quality of life (QOL) of cochlear implantation (CI) for single-sided deafness (SSD) and asymmetric hearing loss (AHL) using the first psychometrically developed CI-specific QOL tool for English-speaking patients and to assess its relationship to objective perceptual measures.STUDY DESIGN: Retrospective cohort study.SETTING: Tertiary-care medical center.PATIENTS: English-speaking adults with SSD or AHL.INTERVENTIONS: Unilateral CI.MAIN OUTCOME MEASURES: Cochlear Implant Quality of Life (CIQOL) score, CI-alone speech-in-quiet (SIQ) score (CNC and AzBio), binaural speech-in-noise (SIN) threshold, binaural azimuthal sound localization (SL) error.RESULTS: At the most recent postoperative evaluation (median, 9.3 months postimplantation), 25 of 28 subjects (89%) had a CIQOL improvement, with the improvement considered clinically beneficial (>3 points) for 18 of 28 subjects (64%). Group-mean CIQOL improvement was observed at the first postoperative visit and did not change significantly thereafter. Objective perceptual measures (SL, SIQ, SIN) continued to improve over 12 months after implantation. Linear mixed-model regression analyses showed a moderate positive correlation between SIN and SIQ improvements (r = 0.50 to 0.59, p < 0.0001) and a strong positive correlation between the improvement in the two SIQ measures (r = 0.89, p < 0.0001). No significant relationships were observed ( p > 0.05) among QOL or the objective perceptual measures.CONCLUSIONS: QOL improved for the majority of subjects implanted for SSD and AHL. Different time courses for improvement in QOL and audiologic tests, combined with the lack of significant relationships among them, suggest that QOL outcomes reflect different aspects of the CI experience than those captured by speech-understanding and localization measures. SIQ may substitute for SIN when clinical constraints exist.

AB - OBJECTIVE: To determine the effect on quality of life (QOL) of cochlear implantation (CI) for single-sided deafness (SSD) and asymmetric hearing loss (AHL) using the first psychometrically developed CI-specific QOL tool for English-speaking patients and to assess its relationship to objective perceptual measures.STUDY DESIGN: Retrospective cohort study.SETTING: Tertiary-care medical center.PATIENTS: English-speaking adults with SSD or AHL.INTERVENTIONS: Unilateral CI.MAIN OUTCOME MEASURES: Cochlear Implant Quality of Life (CIQOL) score, CI-alone speech-in-quiet (SIQ) score (CNC and AzBio), binaural speech-in-noise (SIN) threshold, binaural azimuthal sound localization (SL) error.RESULTS: At the most recent postoperative evaluation (median, 9.3 months postimplantation), 25 of 28 subjects (89%) had a CIQOL improvement, with the improvement considered clinically beneficial (>3 points) for 18 of 28 subjects (64%). Group-mean CIQOL improvement was observed at the first postoperative visit and did not change significantly thereafter. Objective perceptual measures (SL, SIQ, SIN) continued to improve over 12 months after implantation. Linear mixed-model regression analyses showed a moderate positive correlation between SIN and SIQ improvements (r = 0.50 to 0.59, p < 0.0001) and a strong positive correlation between the improvement in the two SIQ measures (r = 0.89, p < 0.0001). No significant relationships were observed ( p > 0.05) among QOL or the objective perceptual measures.CONCLUSIONS: QOL improved for the majority of subjects implanted for SSD and AHL. Different time courses for improvement in QOL and audiologic tests, combined with the lack of significant relationships among them, suggest that QOL outcomes reflect different aspects of the CI experience than those captured by speech-understanding and localization measures. SIQ may substitute for SIN when clinical constraints exist.

U2 - 10.1097/MAO.0000000000003783

DO - 10.1097/MAO.0000000000003783

M3 - Article

C2 - 36728614

SN - 1531-7129

VL - 44

SP - e125-e132

JO - Otology and Neurotology

JF - Otology and Neurotology

IS - 3

ER -

Quality of Life Impact of Cochlear Implantation for Single-Sided Deafness: Assessing the Interrelationship of Objective and Subjective Measures

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