Abstract
Background: Nanotechnology is an emerging field that could have a significant impact on cancer diagnosis, treatment and analysis. Quantum dots represent one of the most interesting nanotechnology-based platforms, and their unique properties make them a potentially versatile tool for molecular diagnostics. Objectives: Here, the most promising uses of quantum dots for translational research are reviewed, ranging from multiplexed immunofluorescence, targeted drug delivery coupled with disease visualization, tumor and sentinel organs localization and long-term cell tracing. Finally, potential future directions for quantum dots as both a diagnostic and therapeutic tool in biomedical research will be explored. Conclusions: The use of quantum dots in biomedical applications is accelerating owing to their unique physical attributes, imaging capabilities, and potential for therapeutic delivery.
| Original language | English |
|---|---|
| Pages (from-to) | 315-322 |
| Number of pages | 8 |
| Journal | Expert Opinion on Medical Diagnostics |
| Volume | 2 |
| Issue number | 3 |
| DOIs | |
| State | Published - Mar 2008 |
Keywords
- Cancer
- Imaging
- Molecular diagnostics
- Proteomics
- Quantum dots
- Reserve-phase array
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