Real-World Effectiveness and Safety of Tofacitinib in Crohn's Disease and IBD-U: A Multicenter Study From the TROPIC Consortium

Marc Fenster; Quazim A. Alayo; Aava Khatiwada; Wenfei Wang; Christina Dimopoulos; Alexandra Gutierrez; Matthew A. Ciorba; George P. Christophi; Robert P. Hirten; Christina Ha; Poonam Beniwal-Patel; Benjamin L. Cohen; Gaurav Syal; Andres Yarur; Anish Patel; Jean Frederic Colombel; Joel Pekow; Ryan C. Ungaro; David T. Rubin; Parakkal Deepak

doi:10.1016/j.cgh.2020.10.025

Real-World Effectiveness and Safety of Tofacitinib in Crohn's Disease and IBD-U: A Multicenter Study From the TROPIC Consortium

Marc Fenster, Quazim A. Alayo, Aava Khatiwada, Wenfei Wang, Christina Dimopoulos, Alexandra Gutierrez, Matthew A. Ciorba, George P. Christophi, Robert P. Hirten, Christina Ha, Poonam Beniwal-Patel, Benjamin L. Cohen, Gaurav Syal, Andres Yarur, Anish Patel, Jean Frederic Colombel, Joel Pekow, Ryan C. Ungaro, David T. Rubin, Parakkal Deepak^*

^*Corresponding author for this work

Research output: Contribution to journal › Short survey › peer-review

22 Scopus citations

Original language	English
Pages (from-to)	2207-2209.e3
Journal	Clinical Gastroenterology and Hepatology
Volume	19
Issue number	10
DOIs	https://doi.org/10.1016/j.cgh.2020.10.025
State	Published - Oct 2021
Externally published	Yes

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10.1016/j.cgh.2020.10.025

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Fenster, M., Alayo, Q. A., Khatiwada, A., Wang, W., Dimopoulos, C., Gutierrez, A., Ciorba, M. A., Christophi, G. P., Hirten, R. P., Ha, C., Beniwal-Patel, P., Cohen, B. L., Syal, G., Yarur, A., Patel, A., Colombel, J. F., Pekow, J., Ungaro, R. C., Rubin, D. T., & Deepak, P. (2021). Real-World Effectiveness and Safety of Tofacitinib in Crohn's Disease and IBD-U: A Multicenter Study From the TROPIC Consortium. Clinical Gastroenterology and Hepatology, 19(10), 2207-2209.e3. https://doi.org/10.1016/j.cgh.2020.10.025

@article{a6c4f7452b8246fbb69749a37786de2f,

title = "Real-World Effectiveness and Safety of Tofacitinib in Crohn's Disease and IBD-U: A Multicenter Study From the TROPIC Consortium",

author = "Marc Fenster and Alayo, {Quazim A.} and Aava Khatiwada and Wenfei Wang and Christina Dimopoulos and Alexandra Gutierrez and Ciorba, {Matthew A.} and Christophi, {George P.} and Hirten, {Robert P.} and Christina Ha and Poonam Beniwal-Patel and Cohen, {Benjamin L.} and Gaurav Syal and Andres Yarur and Anish Patel and Colombel, {Jean Frederic} and Joel Pekow and Ungaro, {Ryan C.} and Rubin, {David T.} and Parakkal Deepak",

note = "Funding Information: Funding Parakkal Deepak is supported by a Junior Faculty Development Award from the American College of Gastroenterology . Matthew A. Ciorba is supported by DK109384, a Crohn{\textquoteright}s and Colitis Foundation Daniel H Present Senior Research Award (Ref. 370763), and philanthropic support from the Givin{\textquoteright} it all for Guts Foundation ( https://givinitallforguts.org ) and the Lawrence C. Pakula MD IBD Research Innovation and Education Fund. Additional grant support for the REDCap database was provided by the Clinical and Translational Science Award (UL1 TR000448) and Siteman Cancer Center Support Grant (P30-CA091842). The content is solely the responsibility of the authors and does not necessarily represent the official views of the Center for Translational Medicine, the National Center for Advancing Translational Sciences, or the National Institutes of Health. Ryan C. Ungaro is supported by a Career Development Award from the Crohn{\textquoteright}s and Colitis Foundation and a National Institutes of Health K23 Career Development Award (K23KD111995-01A1). Robert P. Hirten is supported by a Career Development Award from the Crohn{\textquoteright}s and Colitis Foundation Funding Information: Funding Parakkal Deepak is supported by a Junior Faculty Development Award from the American College of Gastroenterology. Matthew A. Ciorba is supported by DK109384, a Crohn's and Colitis Foundation Daniel H Present Senior Research Award (Ref. 370763), and philanthropic support from the Givin? it all for Guts Foundation (https://givinitallforguts.org) and the Lawrence C. Pakula MD IBD Research Innovation and Education Fund. Additional grant support for the REDCap database was provided by the Clinical and Translational Science Award (UL1 TR000448) and Siteman Cancer Center Support Grant (P30-CA091842). The content is solely the responsibility of the authors and does not necessarily represent the official views of the Center for Translational Medicine, the National Center for Advancing Translational Sciences, or the National Institutes of Health. Ryan C. Ungaro is supported by a Career Development Award from the Crohn's and Colitis Foundation and a National Institutes of Health K23 Career Development Award (K23KD111995-01A1). Robert P. Hirten is supported by a Career Development Award from the Crohn's and Colitis Foundation",

year = "2021",

month = oct,

doi = "10.1016/j.cgh.2020.10.025",

language = "English",

volume = "19",

pages = "2207--2209.e3",

journal = "Clinical Gastroenterology and Hepatology",

issn = "1542-3565",

number = "10",

}

Fenster, M, Alayo, QA, Khatiwada, A, Wang, W, Dimopoulos, C, Gutierrez, A, Ciorba, MA, Christophi, GP, Hirten, RP, Ha, C, Beniwal-Patel, P, Cohen, BL, Syal, G, Yarur, A, Patel, A, Colombel, JF, Pekow, J, Ungaro, RC, Rubin, DT & Deepak, P 2021, 'Real-World Effectiveness and Safety of Tofacitinib in Crohn's Disease and IBD-U: A Multicenter Study From the TROPIC Consortium', Clinical Gastroenterology and Hepatology, vol. 19, no. 10, pp. 2207-2209.e3. https://doi.org/10.1016/j.cgh.2020.10.025

TY - JOUR

T1 - Real-World Effectiveness and Safety of Tofacitinib in Crohn's Disease and IBD-U

T2 - A Multicenter Study From the TROPIC Consortium

AU - Fenster, Marc

AU - Alayo, Quazim A.

AU - Khatiwada, Aava

AU - Wang, Wenfei

AU - Dimopoulos, Christina

AU - Gutierrez, Alexandra

AU - Ciorba, Matthew A.

AU - Christophi, George P.

AU - Hirten, Robert P.

AU - Ha, Christina

AU - Beniwal-Patel, Poonam

AU - Cohen, Benjamin L.

AU - Syal, Gaurav

AU - Yarur, Andres

AU - Patel, Anish

AU - Colombel, Jean Frederic

AU - Pekow, Joel

AU - Ungaro, Ryan C.

AU - Rubin, David T.

AU - Deepak, Parakkal

N1 - Funding Information: Funding Parakkal Deepak is supported by a Junior Faculty Development Award from the American College of Gastroenterology . Matthew A. Ciorba is supported by DK109384, a Crohn’s and Colitis Foundation Daniel H Present Senior Research Award (Ref. 370763), and philanthropic support from the Givin’ it all for Guts Foundation ( https://givinitallforguts.org ) and the Lawrence C. Pakula MD IBD Research Innovation and Education Fund. Additional grant support for the REDCap database was provided by the Clinical and Translational Science Award (UL1 TR000448) and Siteman Cancer Center Support Grant (P30-CA091842). The content is solely the responsibility of the authors and does not necessarily represent the official views of the Center for Translational Medicine, the National Center for Advancing Translational Sciences, or the National Institutes of Health. Ryan C. Ungaro is supported by a Career Development Award from the Crohn’s and Colitis Foundation and a National Institutes of Health K23 Career Development Award (K23KD111995-01A1). Robert P. Hirten is supported by a Career Development Award from the Crohn’s and Colitis Foundation Funding Information: Funding Parakkal Deepak is supported by a Junior Faculty Development Award from the American College of Gastroenterology. Matthew A. Ciorba is supported by DK109384, a Crohn's and Colitis Foundation Daniel H Present Senior Research Award (Ref. 370763), and philanthropic support from the Givin? it all for Guts Foundation (https://givinitallforguts.org) and the Lawrence C. Pakula MD IBD Research Innovation and Education Fund. Additional grant support for the REDCap database was provided by the Clinical and Translational Science Award (UL1 TR000448) and Siteman Cancer Center Support Grant (P30-CA091842). The content is solely the responsibility of the authors and does not necessarily represent the official views of the Center for Translational Medicine, the National Center for Advancing Translational Sciences, or the National Institutes of Health. Ryan C. Ungaro is supported by a Career Development Award from the Crohn's and Colitis Foundation and a National Institutes of Health K23 Career Development Award (K23KD111995-01A1). Robert P. Hirten is supported by a Career Development Award from the Crohn's and Colitis Foundation

PY - 2021/10

Y1 - 2021/10

UR - http://www.scopus.com/inward/record.url?scp=85100538239&partnerID=8YFLogxK

U2 - 10.1016/j.cgh.2020.10.025

DO - 10.1016/j.cgh.2020.10.025

M3 - Short survey

C2 - 33068786

AN - SCOPUS:85100538239

SN - 1542-3565

VL - 19

SP - 2207-2209.e3

JO - Clinical Gastroenterology and Hepatology

JF - Clinical Gastroenterology and Hepatology

IS - 10

ER -

Real-World Effectiveness and Safety of Tofacitinib in Crohn's Disease and IBD-U: A Multicenter Study From the TROPIC Consortium

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