Recent advances in use of fresh frozen plasma, cryoprecipitate, immunoglobulins, and clotting factors for transfusion support in patients with hematologic disease

Prajeeda M. Nair, Matthew J. Rendo, Kristin M. Reddoch-Cardenas, Jason K. Burris, Michael A. Meledeo, Andrew P. Cap*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

13 Scopus citations

Abstract

Hematologic diseases include a broad range of acquired and congenital disorders, many of which affect plasma proteins that control hemostasis and immune responses. Therapeutic interventions for these disorders include transfusion of plasma, cryoprecipitate, immunoglobulins, or convalescent plasma-containing therapeutic antibodies from patients recovering from infectious diseases, as well as concentrated pro- or anticoagulant factors. This review will focus on recent advances in the uses of plasma and its derivatives for patients with acquired and congenital hematologic disorders.

Original languageEnglish
Pages (from-to)73-82
Number of pages10
JournalSeminars in Hematology
Volume57
Issue number2
DOIs
StatePublished - Apr 2020
Externally publishedYes

Keywords

  • Hematologic disease
  • Plasma transfusion
  • Transfusion support

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