TY - JOUR
T1 - Refractory Malignant Eosinophilic Colitis Leading to Ischemic Colitis
AU - Awad, Christina
AU - Bailes, Benjamin
AU - Horn, Christian
AU - Patel, Anish
PY - 2023/2
Y1 - 2023/2
N2 - Eosinophilic colitis (EC) is the most uncommon disease within the spectrum of eosinophilic gastrointestinal disorders. Currently, there are no well-established diagnostic criteria and no approved Food and Drug Administration therapies. We discuss a case of a 30-year-old man with refractory malignant EC leading to ischemic colitis. The patient was tried on multiple therapies, including a combination therapy of benralizumab and vedolizumab, which were unsuccessful. Unfortunately, the patient ultimately required a total proctocolectomy. More studies need to be performed to treat patients with severe refractory cases of EC.
AB - Eosinophilic colitis (EC) is the most uncommon disease within the spectrum of eosinophilic gastrointestinal disorders. Currently, there are no well-established diagnostic criteria and no approved Food and Drug Administration therapies. We discuss a case of a 30-year-old man with refractory malignant EC leading to ischemic colitis. The patient was tried on multiple therapies, including a combination therapy of benralizumab and vedolizumab, which were unsuccessful. Unfortunately, the patient ultimately required a total proctocolectomy. More studies need to be performed to treat patients with severe refractory cases of EC.
UR - https://www.mendeley.com/catalogue/1fcdfcdb-d678-3d97-92d9-c00655f6c1b4/
U2 - 10.14309/crj.0000000000000991
DO - 10.14309/crj.0000000000000991
M3 - Article
SN - 2326-3253
VL - 10
SP - e00991
JO - ACG case reports journal
JF - ACG case reports journal
IS - 2
ER -