Refractory Pseudomonas bacteremia in a 2-year-old sterilized by bacteriophage therapy

C. Duplessis*, B. Biswas, B. Hanisch, M. Perkins, M. Henry, J. Quinones, D. Wolfe, L. Estrella, T. Hamilton

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

77 Scopus citations

Abstract

Here, we report a complex case that involved a pediatric patient who experienced recalcitrant multidrug-resistant Pseudomonas aeruginosa infection complicated by bacteremia/sepsis; our antibacterial options were limited because of resistance, allergies, and suboptimal source control. A cocktail of 2 bacteriophages targeting the infectious organism introduced on 2 separate occasions sterilized the bacteremia.

Original languageEnglish
Pages (from-to)253-256
Number of pages4
JournalJournal of the Pediatric Infectious Diseases Society
Volume7
Issue number3
DOIs
StatePublished - 17 Aug 2018
Externally publishedYes

Keywords

  • Bacteremia
  • Bacteriophage
  • Multidrug resistance
  • Pseudomonas aeruginosa
  • Sepsis

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