Relationship of neural cell adhesion molecules (N-CAMs) with adenylate cyclase

V. M. Lipkin; E. A. Surina; G. V. Petukhova; V. M. Petrov; S. F. Mirzoeva; T. V. Rakitina

doi:10.1016/0014-5793(92)80577-4

Relationship of neural cell adhesion molecules (N-CAMs) with adenylate cyclase

V. M. Lipkin^*
, E. A. Surina
, G. V. Petukhova
, V. M. Petrov
, S. F. Mirzoeva
, T. V. Rakitina

^*Corresponding author for this work

Biochemistry

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Bovine brain cDNA cloned earlier and attributed to calmodulin-independent adenylate cyclase encodes the neural cell adhesion molecule (N-CAM). The expression of N-CAM mRNA in Xenopus laevis oocytes increases their basal adenylate cyclase activity. Polyclonal antibodies against synthetic peptide A, VAENQQGKSKAAHFV (664-678 amino acid residues of bovine N-CAM), containing sequence AXXXXGKS which is homologous to the nucleotide-binding consensus sequence GXXXXGKS, inhibit the adenylate cyclase activity. A close relationship appears to exist between adenylate cyclase and N-CAM.

Original language	English
Pages (from-to)	9-11
Number of pages	3
Journal	FEBS Letters
Volume	304
Issue number	1
DOIs	https://doi.org/10.1016/0014-5793(92)80577-4
State	Published - 8 Jun 1992

Keywords

Adenylate cyclase
Neural cell adhesion molecule

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10.1016/0014-5793(92)80577-4

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title = "Relationship of neural cell adhesion molecules (N-CAMs) with adenylate cyclase",

abstract = "Bovine brain cDNA cloned earlier and attributed to calmodulin-independent adenylate cyclase encodes the neural cell adhesion molecule (N-CAM). The expression of N-CAM mRNA in Xenopus laevis oocytes increases their basal adenylate cyclase activity. Polyclonal antibodies against synthetic peptide A, VAENQQGKSKAAHFV (664-678 amino acid residues of bovine N-CAM), containing sequence AXXXXGKS which is homologous to the nucleotide-binding consensus sequence GXXXXGKS, inhibit the adenylate cyclase activity. A close relationship appears to exist between adenylate cyclase and N-CAM.",

keywords = "Adenylate cyclase, Neural cell adhesion molecule",

author = "Lipkin, \{V. M.\} and Surina, \{E. A.\} and Petukhova, \{G. V.\} and Petrov, \{V. M.\} and Mirzoeva, \{S. F.\} and Rakitina, \{T. V.\}",

year = "1992",

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doi = "10.1016/0014-5793(92)80577-4",

language = "English",

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T1 - Relationship of neural cell adhesion molecules (N-CAMs) with adenylate cyclase

AU - Lipkin, V. M.

AU - Surina, E. A.

AU - Petukhova, G. V.

AU - Petrov, V. M.

AU - Mirzoeva, S. F.

AU - Rakitina, T. V.

PY - 1992/6/8

Y1 - 1992/6/8

N2 - Bovine brain cDNA cloned earlier and attributed to calmodulin-independent adenylate cyclase encodes the neural cell adhesion molecule (N-CAM). The expression of N-CAM mRNA in Xenopus laevis oocytes increases their basal adenylate cyclase activity. Polyclonal antibodies against synthetic peptide A, VAENQQGKSKAAHFV (664-678 amino acid residues of bovine N-CAM), containing sequence AXXXXGKS which is homologous to the nucleotide-binding consensus sequence GXXXXGKS, inhibit the adenylate cyclase activity. A close relationship appears to exist between adenylate cyclase and N-CAM.

AB - Bovine brain cDNA cloned earlier and attributed to calmodulin-independent adenylate cyclase encodes the neural cell adhesion molecule (N-CAM). The expression of N-CAM mRNA in Xenopus laevis oocytes increases their basal adenylate cyclase activity. Polyclonal antibodies against synthetic peptide A, VAENQQGKSKAAHFV (664-678 amino acid residues of bovine N-CAM), containing sequence AXXXXGKS which is homologous to the nucleotide-binding consensus sequence GXXXXGKS, inhibit the adenylate cyclase activity. A close relationship appears to exist between adenylate cyclase and N-CAM.

KW - Adenylate cyclase

KW - Neural cell adhesion molecule

UR - https://www.scopus.com/pages/publications/0026717802

U2 - 10.1016/0014-5793(92)80577-4

DO - 10.1016/0014-5793(92)80577-4

M3 - Article

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AN - SCOPUS:0026717802

SN - 0014-5793

VL - 304

SP - 9

EP - 11

JO - FEBS Letters

JF - FEBS Letters

IS - 1

ER -

Relationship of neural cell adhesion molecules (N-CAMs) with adenylate cyclase

Abstract

Keywords

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